SCHEMBL757840

SCHEMBL757840

CCCC1OC(CO)C(O)C(O)C1O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.48
LGALS3 P17931 2/20 0.48
LGALS9 O00182 1/20 0.48
LGALS8 O00214 1/20 0.48
PYGB P11216 3/20 0.47
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.41
OGA O60502 1/20 0.40
MAPT P10636 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26987277 1.00 LGALS1 (0.48) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL3292990 1.00 LGALS1 (0.48) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL3290529 1.00 LGALS1 (0.48) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL388109 0.98 LGALS1 (0.45) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL17087922 0.98 LGALS1 (0.45) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL23848882 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL8347365 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL12993503 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL14028866 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL16644800 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021188586-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-09-23 WO disclosed
US-10632135-B2 Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-04-28 US disclosed
US-8138227-B2 Method for inhibiting or reversing non-enzymatic glycation TRUSTEES OF DARTMOUTH COLLEGE (US) 2012-03-20 US disclosed
US-20080009547-A1 Method for inhibiting or reversing non-enzymatic glycation TRUSTEES OF DARTMOUTH COLLEGE 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10632135-B2 Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease ICAM1, VCAM1, EPCAM LGALS1 2359/4885LGALS3 2709/4885LGALS9 2197/4885
US-20080009547-A1 Method for inhibiting or reversing non-enzymatic glycation AGER, GLO1, GLA LGALS1 160/4885LGALS3 331/4885LGALS9 414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.