Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | FLT1 | P17948 | 2/20 | 0.69 |
| ▸ | FLT4 | P35916 | 2/20 | 0.69 |
| ▸ | KDR | P35968 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931087 | 0.98 | PTGS2 (0.71) | PTGS2MEN1LMNAKMT2AFLT1 | |
| SCHEMBL790393 | 0.92 | PTGS2 (0.67) | PTGS2MEN1LMNAKMT2AFLT1 | |
| SCHEMBL9176266 | 0.90 | PTGS2 (0.78) | PTGS2KMT2AFLT1FLT4KDR | |
| SCHEMBL7774524 | 0.88 | LMNA (0.72) | PTGS2MEN1LMNAKMT2AFLT1 | |
| SCHEMBL7777675 | 0.86 | LMNA (0.60) | PTGS2MEN1LMNAKMT2AFLT1 | |
| SCHEMBL174010 | 0.86 | FLT1 (0.77) | PTGS2MEN1LMNAKMT2AFLT1 | |
| SCHEMBL10769381 | 0.84 | PTGS2 (0.65) | PTGS2MEN1LMNAKMT2AFLT1 | |
| SCHEMBL7647250 | 0.84 | LMNA (0.74) | PTGS2MEN1LMNAKMT2APTGES | |
| SCHEMBL7774521 | 0.84 | LMNA (0.74) | PTGS2MEN1LMNAKMT2APTGES | |
| SCHEMBL29011132 | 0.84 | FLT1 (0.74) | PTGS2MEN1LMNAKMT2AFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732365-B2 | Enantioselective amination and etherification | YALE UNIVERSITY (US) | 2010-06-08 | — | — | US | disclosed |
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | YALE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
| US-20060199728-A1 | Enantioselective amination and etherification | YALE UNIVERSITY (US) | 2006-09-07 | — | — | US | disclosed |
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | AKR1C3, PCNA, AKR1C4 | PTGS2 2581/4885MEN1 1734/4885LMNA 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.