SCHEMBL7777675

SCHEMBL7777675

Cc1ccc(NC(=S)Nc2ccc(S(=O)(=O)NC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.60
ALDH1A1 P00352 4/20 0.60
HPGD P15428 2/20 0.60
PPARG P37231 1/20 0.58
MAPT P10636 4/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
GPR55 Q9Y2T6 1/20 0.57
PTGS2 P35354 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
FLT1 P17948 1/20 0.56
FLT4 P35916 1/20 0.56
KDR P35968 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
PLK1 P53350 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774529 0.96 LMNA (0.63) LMNAALDH1A1HPGDPPARGMAPT
SCHEMBL8658570 0.93 PTGS2 (0.61) LMNAALDH1A1HPGDMAPTNPC1
SCHEMBL6295729 0.92 MEN1 (0.61) LMNAALDH1A1MAPTNPC1RAB9A
SCHEMBL7774524 0.89 LMNA (0.72) LMNAALDH1A1PPARGMAPTNPC1
SCHEMBL7776308 0.89 MAPT (0.61) LMNAALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL8658192 0.89 ALDH1A1 (0.56) LMNAALDH1A1HPGDMAPTNPC1
SCHEMBL8659782 0.88 GAA (0.56) LMNAALDH1A1HPGDMAPTGPR55
SCHEMBL5931087 0.87 PTGS2 (0.71) LMNAALDH1A1PTGS2NPSR1MEN1
SCHEMBL7770066 0.87 MAPT (0.55) LMNAALDH1A1HPGDMAPTNPC1
SCHEMBL3292237 0.86 PTGS2 (0.69) LMNAALDH1A1PTGS2NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed