Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812840 | 0.90 | LMNA (0.52) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| SCHEMBL3757540 | 0.88 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| Barium SCHEMBL2592652 | 0.88 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| SCHEMBL16345225 | 0.88 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| SCHEMBL8210573 | 0.84 | TSHR (0.48) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| SCHEMBL594011 | 0.84 | TSHR (0.54) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| SCHEMBL6975491 | 0.83 | TSHR (0.46) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6291878 | 0.82 | — | — | |
| Ethylene Glycol SCHEMBL11791402 | 0.82 | LMNA (0.50) | LMNAPOLBALDH1A1TSHRPRMT5 | |
| SCHEMBL247203 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131358-A1 | In-Situ Polymer Blend for a Tire | SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2020-04-30 | — | — | US | claimed |
| WO-2019020417-A1 | IN-SITU POLYMER BLEND FOR A TIRE | TRINSEO EUROPE GMBH (CH) | 2019-01-31 | — | — | WO | claimed |
| EP-3434697-A1 | IN-SITU POLYMER BLEND FOR A TIRE | Trinseo Europe GmbH (CH) | 2019-01-30 | — | — | EP | claimed |
| WO-2023099462-A1 | AMINE-CONTAINING VINYLDISILOXANES IN THE MANUFACTURE OF ELASTOMERIC POLYMERS | TRINSEO EUROPE GMBH (CH) | 2023-06-08 | — | — | WO | disclosed |
| EP-4186911-A1 | AMINE-CONTAINING VINYLDISILOXANES IN THE MANUFACTURE OF ELASTOMERIC POLYMERS | Trinseo Europe GmbH (CH) | 2023-05-31 | — | — | EP | disclosed |
| US-11555109-B2 | In-situ polymer blend for a tire | TRINSEO EUROPE GMBH (CH) | 2023-01-17 | — | — | US | disclosed |
| US-10954330-B2 | Use of specific aminosilyl monomers in the manufacture of rubber | TRINSEO EUROPE GMBH (CH) | 2021-03-23 | — | — | US | disclosed |
| US-10858377-B2 | Multivinylaminosilanes as branching agents for functionalized elastomeric polymers | TRINSEO EUROPE GMBH (CH) | 2020-12-08 | — | — | US | disclosed |
| US-20200377636-A1 | Use of Specific Aminosilyl Monomers in the Manufacture of Rubber | SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2020-12-03 | — | — | US | disclosed |
| US-10787562-B2 | Silane-mediated enhancement of rubber storage stability | TRINSEO EUROPE GMBH (CH) | 2020-09-29 | — | — | US | disclosed |
| US-20200131358-A1 | In-Situ Polymer Blend for a Tire | SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2020-04-30 | — | — | US | disclosed |
| EP-0924227-B1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-20030125448-A1 | A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-07-03 | — | — | US | disclosed |
| EP-1318172-A1 | Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| US-20030100683-A1 | Hydrogenated modified polymer, process for producing the same and composition containing the same | JSR CORPORATION (JP) | 2003-05-29 | — | — | US | disclosed |
| EP-1245585-A2 | Hydrogenated modified polymer, process for producing the same and composition containing the same | JSR Corporation (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6362272-B1 | CONJUGATED DIOLEFIN AND AROMATIC VINYL COPOLYMER | JSR CORPORATION (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6191234-B1 | CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD | JSR CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0992537-A1 | Oil extended rubber and rubber composition | JSR Corporation (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0924227-A1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR Corporation (JP) | 1999-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858377-B2 | Multivinylaminosilanes as branching agents for functionalized elastomeric polymers | GMNN, GNE, MSN | LMNA 1313/4885POLB 1534/4885ALDH1A1 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.