Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.67 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.67 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.67 |
| ▸ | CTSB | P07858 | 6/20 | 0.62 |
| ▸ | CTSK | P43235 | 9/20 | 0.61 |
| ▸ | CTSL | P07711 | 5/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3291391 | 1.00 | PSMB1 (0.67) | PSMB1PSMB5PSMB2CTSBCTSK | |
| SCHEMBL3327332 | 1.00 | PSMB1 (0.67) | PSMB1PSMB5PSMB2CTSBCTSK | |
| SCHEMBL3054703 | 0.90 | PSMB1 (0.78) | PSMB1PSMB5PSMB2CTSBCTSK | |
| SCHEMBL8971981 | 0.90 | PSMB1 (0.78) | PSMB1PSMB5PSMB2CTSBCTSK | |
| SCHEMBL1014661 | 0.90 | PSMB1 (0.78) | PSMB1PSMB5PSMB2CTSBCTSK | |
| SCHEMBL7710728 | 0.90 | PSMB1 (0.78) | PSMB1PSMB5PSMB2CTSBCTSK | |
| SCHEMBL14341578 | 0.89 | PSMB1 (0.61) | PSMB1PSMB5PSMB2CTSBCTSK | |
| Mg-132 SCHEMBL14579851 | 0.89 | PSMB1 (0.77) | PSMB1PSMB5PSMB2CTSBCTSK | |
| Mg-132 SCHEMBL2522088 | 0.89 | PSMB1 (0.77) | PSMB1PSMB5PSMB2CTSBCTSK | |
| Mg-132 SCHEMBL13436259 | 0.89 | PSMB1 (0.77) | PSMB1PSMB5PSMB2CTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656782-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2020-05-27 | — | — | EP | disclosed |
| US-7727956-B2 | Deoxonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-7727956-B2 | Deoxonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-7727956-B2 | Deoxonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2010-06-01 | — | — | US | disclosed |
| EP-1805212-B1 | DESOXO-NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-06-10 | — | — | EP | disclosed |
| US-20080058253-A1 | Deoxononadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058253-A1 | Deoxononadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058253-A1 | Deoxononadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-03-06 | — | — | US | disclosed |
| EP-1805212-A1 | DESOXO-NONADEPSIPEPTIDES | AiCuris GmbH & Co. KG (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006042655-A1 | DESOXO-NONADEPSIPEPTIDES | AICURIS GMBH & CO. KG (DE) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058253-A1 | Deoxononadepsipeptides | VIP, DNPEP, NPPA | PSMB1 3716/4885PSMB5 3452/4885PSMB2 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.