SCHEMBL3296107

SCHEMBL3296107

CCCCOc1cccc(CC)c1[SiH](O[SiH](c1c(CC)cccc1OCCCC)c1c(CC)cccc1OCCCC)c1c(CC)cccc1OCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.45
MAPT P10636 3/20 0.45
HPGD P15428 1/20 0.45
ATM Q13315 1/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CSNK1A1 P48729 1/20 0.41
CSNK1D P48730 1/20 0.41
PRKCD Q05655 1/20 0.41
PAK1 Q13153 1/20 0.41
CAMK2B Q13554 1/20 0.41
CAMK2G Q13555 1/20 0.41
CAMK2D Q13557 1/20 0.41
TAOK1 Q7L7X3 1/20 0.41
MCHR1 Q99705 1/20 0.40
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3297756 0.88 CYP1A2 (0.52) MAPTCYP1A2CYP2C9CYP2C19CSNK1A1
SCHEMBL3296614 0.85 MAPT (0.51) L3MBTL1MAPTATMNPSR1ALDH1A1
SCHEMBL3296216 0.82 CYP1A2 (0.46) MAPTCYP1A2CYP2C9CYP2C19MCHR1
SCHEMBL3296644 0.80 ALOX5 (0.40) L3MBTL1MAPTHPGDATMTSHR
SCHEMBL3301704 0.78 GABRA1 (0.46) L3MBTL1MAPTNPSR1TP53
SCHEMBL3297597 0.78 CYP1A2 (0.42) CYP1A2CYP2C9CYP2C19NPSR1TSHR
SCHEMBL9689273 0.77 L3MBTL1 (0.69) L3MBTL1MAPTHPGDATMCYP1A2
SCHEMBL3296201 0.75 LMNA (0.41) L3MBTL1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL11941063 0.75 CNR1 (0.51) L3MBTL1MAPTHPGDATMCYP1A2
SCHEMBL10665768 0.75 CYP1A2 (0.58) L3MBTL1MAPTHPGDATMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 L3MBTL1 1173/4885MAPT 2685/4885HPGD 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.