SCHEMBL3299074

SCHEMBL3299074

O=c1cc(NCc2ccccc2)n(Cc2ccccc2)c(=O)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.59
ALDH1A1 P00352 3/20 0.59
CYP3A4 P08684 1/20 0.59
KMT2A Q03164 3/20 0.55
KDM4E B2RXH2 3/20 0.55
MAPT P10636 2/20 0.55
MEN1 O00255 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.49
RECQL P46063 1/20 0.47
XDH P47989 1/20 0.46
GPR84 Q9NQS5 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CDC25B P30305 1/20 0.44
FABP4 P15090 1/20 0.44
TYMP P19971 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25130124 0.76 HPGD (0.68) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL1032784 0.74 HPGD (1.00) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL4480638 0.74 HPGD (0.66) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL2337883 0.73 HPGD (0.58) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL7563397 0.72 GPR84 (0.73) GPR84CDC25BTYMP
SCHEMBL3802542 0.72 ALDH1A1 (0.62) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL29115280 0.71 HPGD (0.60) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL7434388 0.71 KDM4E (0.67) HPGDALDH1A1CYP3A4KMT2AKDM4E
SCHEMBL22639826 0.70 SMN1; SMN2 (0.74) HPGDALDH1A1KMT2AKDM4EMAPT
SCHEMBL27734946 0.69 HPGD (0.56) HPGDKMT2AKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741390-B2 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2010-06-22 US disclosed
US-20090306257-A1 Stabilizer System for Halogenated Polymers CATENA ADDITIVES GMBH & CO. KG (DE) 2009-12-10 US disclosed
US-20090131564-A1 COORDINATION-POLYMERIC TRIETHANOLAMINEPERCHLORATO(TRIFLATO)METAL INNER COMPLEXES AS ADDITIVES FOR SYNTHETIC POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2009-05-21 US disclosed
US-20090105387-A1 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2009-04-23 US disclosed
EP-1771507-A2 STABILISER SYSTEM FOR HALOGENATED POLYMERS Artemis Research GmbH & Co.KG (DE) 2007-04-11 EP disclosed
WO-2006013040-A2 STABILISER SYSTEM FOR HALOGENATED POLYMERS ARTEMIS RESEARCH GMBH & CO. KG (DE) 2006-02-09 WO disclosed