Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226124 | 0.93 | HTT (0.63) | NPC1ALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL4032340 | 0.85 | NPC1 (0.66) | NPC1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| Methyl Alcohol SCHEMBL3883089 | 0.82 | CES1 (0.58) | ALDH1A1SMN1; SMN2MAPTHTTCTBP2 | |
| Ethane SCHEMBL10956080 | 0.82 | CES1 (0.58) | ALDH1A1SMN1; SMN2MAPTHTTCTBP2 | |
| SCHEMBL27293995 | 0.82 | CES1 (0.64) | ALDH1A1MAPTHTTCTBP2TDP1 | |
| SCHEMBL1493 | 0.82 | CES1 (0.64) | ALDH1A1MAPTHTTCTBP2TDP1 | |
| SCHEMBL5563462 | 0.81 | SRD5A2 (0.62) | LTA4H | |
| SCHEMBL224149 | 0.81 | ALOX5 (0.65) | ALOX5 | |
| Hydrogen Sulfide SCHEMBL27809609 | 0.80 | CES1 (0.61) | ALDH1A1MAPTHTTCTBP2TDP1 | |
| Hydrochloric Acid SCHEMBL3047868 | 0.80 | CES1 (0.61) | ALDH1A1MAPTHTTCTBP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741337-B2 | Azonafide derivatives, methods for their production and pharmaceutical compositions therefrom | UNIBIOSCREEN S.A. (BE) | 2010-06-22 | — | — | US | disclosed |
| US-20080292585-A1 | Azonafide Derivatives, Methods for Their Production and Pharmaceutical Compositions Therefrom | UNIBIOSCREEN S.A. (BE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292585-A1 | Azonafide Derivatives, Methods for Their Production and Pharmaceutical Compositions Therefrom | AADAC, NOTUM, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | NPC1 592/4885ALDH1A1 121/4885RAB9A 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.