SCHEMBL329996

SCHEMBL329996

Cc1cc(=O)oc2c(F)c(OP(=O)(O)O)c(F)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.41
SRC P12931 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
MCL1 Q07820 4/20 0.39
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 4/20 0.38
LMNA P02545 3/20 0.38
GAA P10253 3/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 2/20 0.38
MAPT P10636 2/20 0.38
MAOB P27338 1/20 0.38
MGAM O43451 1/20 0.38
TP53 P04637 1/20 0.38
SI P14410 1/20 0.38
ALOX15 P16050 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
HTT P42858 2/20 0.38
CYP1A2 P05177 2/20 0.38
HTR2C P28335 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446704 1.00 MAOA (0.41) MAOASRCL3MBTL1MCL1KDM4E
Ammonia Solution, Strong SCHEMBL629298 0.99 L3MBTL1 (0.41) MAOASRCL3MBTL1MCL1KDM4E
SCHEMBL27739739 0.87 KDM4E (0.42) MAOASRCL3MBTL1MCL1KDM4E
SCHEMBL14534729 0.84 KDM4E (0.40) L3MBTL1MCL1KDM4EALDH1A1LMNA
SCHEMBL3489922 0.82 KDM4E (0.41) MAOAL3MBTL1MCL1KDM4EALDH1A1
SCHEMBL10265067 0.81 MAOA (0.52) MAOAL3MBTL1MCL1KDM4EALDH1A1
SCHEMBL27353376 0.81 MAOA (0.42) MAOAL3MBTL1MCL1KDM4EALDH1A1
Phosphoric Acid SCHEMBL1934555 0.79 MCL1 (0.50) MAOAL3MBTL1MCL1KDM4EALDH1A1
SCHEMBL2292509 0.78 ALPL (0.44) MAOAL3MBTL1MCL1KDM4EALDH1A1
SCHEMBL10205344 0.78 KDM4E (0.46) MAOAL3MBTL1MCL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637776-A1 USE OF DUPD1 INHIBITORS IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND METABOLIC DISORDERS The Governing Council of the University of Toronto (CA) 2025-10-29 EP claimed
US-12275782-B2 Means and methods for the determination of the biological activity of neurotoxin polypeptides in cells MERZ PHARMA GMBH & CO. KGAA (DE) 2025-04-15 US claimed
EP-4520824-A1 DEOXYRIBOZYME THAT GENERATES FLUORESCENCE AND USES THEREOF Ústav organické chemie a biochemie Akademie ved Ceske Republiky, v.v.i. (CZ) 2025-03-12 EP claimed
US-20240270833-A1 Means and Methods for the Determination of the Biological Activity of Neurotoxin Polypeptides in Cells MERZ PHARMA GMBH & CO. KGAA (DE) 2024-08-15 US claimed
WO-2024130444-A1 USE OF DUPD1 INHIBITORS IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE AND METABOLIC DISORDERS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-06-27 WO claimed
US-11976110-B2 Means and methods for the determination of the biological activity of neurotoxin polypeptides in cells MERZ PHARMA GMBH & CO. KGAA (DE) 2024-05-07 US claimed
US-10900955-B2 Means and methods for the determination of the biological activity of BoNT/E in cells MERZ PHARMA GMBH & CO. KGAA 2021-01-26 US claimed
EP-3233911-B1 MEANS AND METHODS FOR THE DETERMINATION OF THE BIOLOGICAL ACTIVITY OF BONT/E IN CELLS MERZ PHARMA GMBH & CO KGAA (DE) 2020-10-14 EP claimed
US-10605803-B2 Composition for enzyme immunoassay using immunofluorescence and uses thereof BIOMERIEUX (FR) 2020-03-31 US claimed
US-20190023771-A1 MEANS AND METHODS FOR THE DETERMINATION OF THE BIOLOGICAL ACTIVITY OF BONT/E IN CELLS MERZ PHARMA GMBH & CO. KGAA (DE) 2019-01-24 US claimed
US-20030162213-A1 Terminal-phosphate-labeled nucleotides and methods of use GLOBAL LIFE SCIENCES SOLUTIONS USA LLC 2003-08-28 US claimed
US-20030158083-A1 Method of effecting angiogenesis by modulating the function of a novel endothelia phosphatase THE PROCTER & GAMBLE COMPANY 2003-08-21 US claimed
WO-2003056029-A2 HIGHLY SENSITIVE AND CONTINUOUS PROTEIN-TYROSINE-PHOSPHATASE (PTPASE) TEST USING 6,8 DIFLUORO-4-METHYL-UMBELLIFERYLPHOSPHATE AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-07-10 WO claimed
US-20030124576-A1 Such as (3-cyanocoumarinyl)dideoxyadenosine-5'-triphosphate which reacts with phosophatase to create detectable species (chemiluminescence, fluorescence); substrates for nucleic acid polymerases GLOBAL LIFE SCIENCES SOLUTIONS USA LLC 2003-07-03 US claimed
US-20030096253-A1 Single nucleotide amplification and detection by polymerase GLOBAL LIFE SCIENCES SOLUTIONS USA LLC 2003-05-22 US claimed
US-20030077610-A1 Terminal-phosphate-labeled nucleotides and methods of use GLOBAL LIFE SCIENCES SOLUTIONS USA LLC 2003-04-24 US claimed
WO-2003031930-A2 A PHOSPHATASE ASSOCIATED WITH METASTASIS THE JOHNS HOPKINS UNIVERSITY (US) 2003-04-17 WO claimed
WO-2003020984-A2 TERMINAL-PHOSPHATE-LABELED NUCLEOTIDES AND METHODS OF USE AMERSHAM BIOSCIENCES CORP (US) 2003-03-13 WO claimed
WO-2003020734-A2 LABELED NUCLEOSIDE POLYPHOSPHATES AMERSHAM BIOSCIENCES CORP (US) 2003-03-13 WO claimed
WO-2003020891-A2 SINGLE NUCLEOTIDE AMPLIFICATION AND DETECTION BY POLYMERASE AMERSHAM BIOSCIENCES CORP (US) 2003-03-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030124576-A1 Such as (3-cyanocoumarinyl)dideoxyadenosine-5'-triphosphate which reacts with phosophatase to create detectable species (chemiluminescence, fluorescence); substrates for nucleic acid polymerases PNP, RNGTT, MTAP MAOA 2036/4885SRC 3967/4885L3MBTL1 2211/4885
US-20030077610-A1 Terminal-phosphate-labeled nucleotides and methods of use RNGTT, DNTT, PNP MAOA 2612/4885SRC 3348/4885L3MBTL1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.