Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610104 | 0.80 | IDO1 (0.48) | IDO1PYCR1L3MBTL1TYRRAB9A | |
| SCHEMBL27674021 | 0.80 | NOS3 (0.41) | IDO1 | |
| SCHEMBL9642338 | 0.79 | IDO1 (0.52) | IDO1PYCR1L3MBTL1TYRRAB9A | |
| SCHEMBL1611733 | 0.78 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL10729588 | 0.78 | IDO1 (0.56) | IDO1PYCR1L3MBTL1TYRRAB9A | |
| SCHEMBL3956146 | 0.78 | IDO1 (0.56) | IDO1PYCR1L3MBTL1TYRRAB9A | |
| SCHEMBL11341386 | 0.77 | IDO1 (0.68) | IDO1PYCR1L3MBTL1TYRRAB9A | |
| SCHEMBL1610592 | 0.77 | IDO1 (0.45) | IDO1PYCR1L3MBTL1RAB9ANPC1 | |
| SCHEMBL104124 | 0.76 | TYR (0.58) | IDO1TYRRAB9ANPC1HTT | |
| SCHEMBL1803971 | 0.76 | ESR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| WO-2022128832-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | claimed |
| EP-2407511-B1 | Thermoplastic resin composition | CHEIL IND INC (KR) | 2017-03-22 | — | — | EP | claimed |
| CN-102250458-B | Poly carbonate resin composition and moulded product thereof | CHEIL INDUSTRIES INC. (KR) | 2016-01-27 | — | — | CN | claimed |
| US-8557912-B2 | Thermoplastic resin composition | CHEIL INDUSTRIES INC. (KR) | 2013-10-15 | — | — | US | claimed |
| EP-2582409-A1 | HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS | Novartis AG (CH) | 2013-04-24 | — | — | EP | claimed |
| US-20120016068-A1 | Thermoplastic Resin Composition | CHEIL INDUSTRIES INC. (KR) | 2012-01-19 | — | — | US | claimed |
| EP-2407511-A1 | Thermoplastic resin composition | Cheil Industries Inc. (KR) | 2012-01-18 | — | — | EP | claimed |
| WO-2011163126-A1 | HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS | NOVARTIS AG (CH) | 2011-12-29 | — | — | WO | claimed |
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | claimed |
| US-6699855-B2 | PYRROLOPYRAZINONES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2004-03-02 | — | — | US | claimed |
| EP-1177227-B1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORP (US) | 2003-10-01 | — | — | EP | claimed |
| US-20020128417-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-09-12 | — | — | US | claimed |
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-05-30 | — | — | US | claimed |
| EP-1177227-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2002-02-06 | — | — | EP | claimed |
| US-20020007032-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-01-17 | — | — | US | claimed |
| US-20010056165-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2001-12-27 | — | — | US | claimed |
| US-6281319-B1 | HYDRATABLE POLYMER | SURGIDEV CORPORATION | 2001-08-28 | — | — | US | claimed |
| WO-2000061646-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2000-10-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065248-A1 | Inhibitors of hepatitis C virus NS3 protease | TMPRSS15, CTRC, CPN1 | IDO1 1672/4885PYCR1 1252/4885L3MBTL1 2982/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | IDO1 3006/4885PYCR1 642/4885L3MBTL1 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.