SCHEMBL330047

SCHEMBL330047

COC([SiH3])C(OC)(OC)c1ccncc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL151772 0.80 KCNN4 (0.37)
SCHEMBL574709 0.74 PGK1 (0.31)
SCHEMBL329528 0.70 KMT2A (0.30)
SCHEMBL5858729 0.66 USP2 (0.42)
SCHEMBL6582778 0.62 USP2 (0.42) CYP3A4KIF11
SCHEMBL28443995 0.62 KIF11 (0.68) KIF11
SCHEMBL27526789 0.61 KIF11 (0.52) CYP3A4KIF11
SCHEMBL6182586 0.60 LOXL2 (0.38) CYP3A4KIF11
SCHEMBL574402 0.59
SCHEMBL65312 0.59 KIF11 (0.71) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2407507-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORP (JP) 2016-09-28 EP disclosed
EP-2407507-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR Corporation (JP) 2012-01-18 EP disclosed
US-20110319519-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORPORATION (JP) 2011-12-29 US disclosed