Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.66 |
| ▸ | PTPN6 | P29350 | 5/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.66 |
| ▸ | PGK1 | P00558 | 2/20 | 0.57 |
| ▸ | PGK2 | P07205 | 2/20 | 0.57 |
| ▸ | PTPRB | P23467 | 3/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330067 | 0.84 | PTPN1 (0.70) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL4316970 | 0.80 | PTPN1 (1.00) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL13372416 | 0.79 | PTPN1 (0.62) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL19696719 | 0.74 | PTPN1 (0.70) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL19696718 | 0.74 | PTPN1 (0.81) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL3385203 | 0.73 | PTPN1 (0.66) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL12682225 | 0.73 | PGK1 (0.64) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL20672233 | 0.73 | PTPN1 (0.78) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL7535721 | 0.73 | PGK1 (0.69) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL3736057 | 0.73 | PTPN1 (0.62) | PTPN1PTPN2PTPN6PTPN11PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925504-B2 | Compartmentalised combinatorial chemistry by microfluidic control | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-03-27 | — | — | US | disclosed |