Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL2252165 | 0.87 | TDP1 (0.50) | TDP1TSHRALDH1A1MAPK1 | |
| Glycerin SCHEMBL132749 | 0.84 | LMNA (0.56) | TDP1TSHRALDH1A1LMNA | |
| Glycerin SCHEMBL4251336 | 0.84 | LMNA (0.56) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL8927831 | 0.83 | TDP1 (0.46) | TDP1 | |
| Propylene Glycol SCHEMBL3535 | 0.82 | — | — | |
| Propylene Glycol SCHEMBL7522896 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAMAPK1 | |
| Propylene Glycol SCHEMBL55583 | 0.82 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAMAPK1 | |
| Propylene Glycol SCHEMBL28578 | 0.82 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.82 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115810753-B | Composition for preparing negative electrode protective film, negative electrode protective film and preparation method thereof, lithium battery negative electrode and lithium battery | 比亚迪股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119613726-A | Vinyl silicone oil for platinum catalytic system and preparation method thereof | 湖北兴瑞硅材料有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119546144-A | Film and preparation method thereof, light-emitting device and preparation method thereof, and display device | 广东聚华印刷显示技术有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-118109122-A | Epoxy silicone oil emulsion for coating and preparation method thereof | 曲敏丽 | 2024-05-31 | — | — | CN | claimed |
| CN-117747435-A | Precursor solution for surface energy directional assembly processing technology and preparation method thereof | 清华大学 | 2024-03-22 | — | — | CN | claimed |
| CN-115247013-A | Aqueous coating composition with high storage stability | 廊坊立邦涂料有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-111370495-B | Thin film transistor active layer ink and preparation method of thin film transistor | TCL科技集团股份有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-113372756-A | Paint remover for ABS plastic base material and preparation method and use method thereof | 万辉(广州)高新材料有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-113248978-A | Ink, thin film transistor and preparation method thereof, active layer thin film and display device | 广东聚华印刷显示技术有限公司 | 2021-08-13 | — | — | CN | claimed |
| US-11083192-B2 | Fertilizer and agrochemical formulation | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-08-10 | — | — | US | claimed |
| US-5147717-A | Transparent image-recording elements | EASTMAN KODAK COMPANY (US) | 1992-09-15 | — | — | US | claimed |
| US-5139867-A | Ink jet recording transparency | EASTMAN KODAK COMPANY (US) | 1992-08-18 | — | — | US | claimed |
| US-5126193-A | Ink jet recording sheet | EASTMAN KODAK COMPANY (US) | 1992-06-30 | — | — | US | claimed |
| US-5069718-A | Potassium substituted inks for ink-jet printers | HEWLETT-PACKARD COMPANY (US) | 1991-12-03 | — | — | US | claimed |
| US-4786327-A | Dye preparation for thermal ink-jet printheads using ion exchange | HEWLETT-PACKARD COMPANY (US) | 1988-11-22 | — | — | US | claimed |
| EP-0262821-A2 | Dye preparation for thermal ink-jet printheads using a one step ion exchange process | Hewlett-Packard Company (US) | 1988-04-06 | — | — | EP | claimed |
| US-4413148-A | REACTION OF CUMENE HYDROPEROXIDE AND DIMETHYLBENZYLMLCOHOL | NIPPON OIL AND FATS CO., LTD. (JP) | 1983-11-01 | — | — | US | claimed |
| US-4230609-A | INTERPOLYMER OF A HYDROPHOBIC MONOMER; AN ACRYLATE, VINYL ETHER, OR DIENE; AND HYDROPHILIC MONOMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4124555-A | FILM FORMING | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| US-4031158-A | LUBRICANT, COSMETICS, TEXTILES | LION FAT & OIL CO., LTD. (JA) | 1977-06-21 | — | — | US | claimed |