Glycerin

Glycerin

SCHEMBL4251336

CC(C)OC(C)C.OCC(O)CO.OCC(O)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
ALDH1A1 P00352 1/20 0.56
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 3/20 0.39
THRB P10828 1/20 0.38
USP2 O75604 1/20 0.33
CYP1A2 P05177 2/20 0.30
KDM4E B2RXH2 1/20 0.30
AGTR1 P30556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL132749 1.00 LMNA (0.56) LMNAALDH1A1TDP1TSHRTHRB
Glycerin SCHEMBL27588266 0.92 LMNA (0.47) LMNAALDH1A1TDP1TSHRTHRB
Propylene Glycol SCHEMBL330160 0.84 TDP1 (0.67) LMNAALDH1A1TDP1TSHR
Glycerin SCHEMBL1081867 0.79 LMNA (0.75) LMNAALDH1A1TDP1TSHRTHRB
Glycerin SCHEMBL8328338 0.79 LMNA (0.75) LMNAALDH1A1TDP1TSHRTHRB
Glycerin SCHEMBL7624987 0.79 LMNA (0.75) LMNAALDH1A1TDP1TSHRTHRB
Glycerin SCHEMBL28830316 0.79 LMNA (0.53) LMNAALDH1A1TDP1TSHRTHRB
Isobutanol SCHEMBL23751338 0.78 TSHR (0.60) TDP1TSHR
Isopropyl Alcohol SCHEMBL8675755 0.78 TSHR (0.40) LMNAALDH1A1TDP1TSHR
Isopropyl Alcohol SCHEMBL6672907 0.78 TSHR (0.40) LMNAALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7235229-B2 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients THE PROCTER & GAMBLE COMPANY (US) 2007-06-26 US claimed
CN-1713887-A Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients PROCTER & GAMBLE (US) 2005-12-28 CN claimed
CN-1221242-C Compositions containing solubilized acid-enhanced antiperspirant active PROCTER & GAMBLE (US) 2005-10-05 CN claimed
EP-1562541-A1 CLEAR, STABLE, DRY-AND-NON-STICKY ANTIPERSPIRANT HAVING A SELECT GROUP OF POLAR SILICONE EMOLLIENTS THE PROCTER & GAMBLE COMPANY (US) 2005-08-17 EP claimed
US-20040247546-A1 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients THE PROCTER & GAMBLE COMPANY 2004-12-09 US claimed
WO-2004047786-A1 CLEAR, STABLE, DRY-AND-NON-STICKY ANTIPERSPIRANT HAVING A SELECT GROUP OF POLAR SILICONE EMOLLIENTS THE PROCTER & GAMBLE COMPANY (US) 2004-06-10 WO claimed
US-20030026773-A1 Anhydrous liquid antiperspirant emulsions THE PROCTER & GAMBLE COMPANY 2003-02-06 US claimed
WO-2003002082-A1 PRESSURIZED ANHYDROUS ANTIPERSPIRANT EMULSIONS THE PROCTER & GAMBLE COMPANY (US) 2003-01-09 WO claimed
US-20030007935-A1 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A LOW POLARITY SOLVENT THE PROCTER & GAMBLE COMPANY 2003-01-09 US claimed
US-6485715-B1 Stable pressurized antiperspirant compositions containing dimethylether propellant and a low polarity solvent THE PROCTOR & GAMBLE COMPANY 2002-11-26 US claimed
CN-1376047-A Compositions containing solubilized acid-enhanced antiperspirant active PROCTER & GAMBLE (US) 2002-10-23 CN claimed
CN-1371269-A Compositions containing solubilized antiperspirant active PROCTER & GAMBLE (US) 2002-09-25 CN claimed
US-6416750-B1 MIXING ALUMINUM CHLOROHYDRATE, WATER, AND DIOL SOLVENT, SPRAY DRYING TO FORM POWDER, AND DISSOLVING INTO 1,2-DIOL SOLVENT (1,2-HEXANEDIOL); INCREASED FORMULATION FLEXIBILITY; LESS ENERGY INTENSIVE PROCESS SOMERVILLE TECHNOLOGY GROUP, INC. 2002-07-09 US claimed
US-6399049-B1 LIQUID 1,2-HYDROXYALKYL AMIDE, ESTER, ETHER, SILICONE OR ALKYL COMPOUND CARRIERS; NONIRRITATING; THE PROCTER & GAMBLE COMPANY 2002-06-04 US claimed
EP-1206238-A2 COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP claimed
EP-1206237-A1 COMPOSITIONS CONTAINING SOLUBILIZED, ACID-ENHANCED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP claimed
WO-2001013869-A2 COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO claimed
WO-2001013872-A1 COMPOSITIONS CONTAINING SOLUBILIZED, ACID-ENHANCED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO claimed
US-6126928-A Compositions containing solubilized, acid-enhanced antiperspirant active THE PROCTER & GAMBLE COMPANY (US) 2000-10-03 US claimed
EP-2492301-B1 NOVEL CO-MODIFIED ORGANOPOLYSILOXANE DOW TORAY CO LTD (JP) 2023-03-29 EP disclosed
US-9580600-B2 Thickening or gelling agent for oily raw materials DOW CONRING TORAY CO., LTD. (JP) 2017-02-28 US disclosed
US-8784787-B2 Co-modified organopolysiloxane DOW CORNING TORAY CO., LTD. (JP) 2014-07-22 US disclosed
EP-2492333-B1 THICKENING OR GELLING AGENT FOR OILY RAW MATERIALS DOW CORNING TORAY CO LTD (JP) 2014-04-30 EP disclosed
US-20120269875-A1 Novel Co-Modified Organopolysiloxane DOW TORAY CO., LTD. (JP) 2012-10-25 US disclosed
US-20120269748-A1 Thickening Or Gelling Agent For Oily Raw Materials DOW TORAY CO., LTD. (JP) 2012-10-25 US disclosed
EP-2492301-A1 NOVEL CO-MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2012-08-29 EP disclosed
EP-2492333-A1 THICKENING OR GELLING AGENT FOR OILY RAW MATERIALS Dow Corning Toray Co., Ltd. (JP) 2012-08-29 EP disclosed
US-7905673-B2 Antiperspirant composition and applicator therefor THE PROCTER & GAMBLE COMPANY (US) 2011-03-15 US disclosed
US-20090130029-A1 GLYCEROL ETHERS VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF FOAMIX LTD. (IL) 2009-05-21 US disclosed
US-7344707-B2 Low combustion aerosol products in plastic packages having a reduced fire hazard classification that subsequently reduces storage costs THE PROCTER & GAMBLE COMPANY (US) 2008-03-18 US disclosed
US-7235229-B2 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients THE PROCTER & GAMBLE COMPANY (US) 2007-06-26 US disclosed
EP-1694283-A1 ANTIPERSPIRANT COMPOSITION AND APPLICATOR THEREFOR THE PROCTER & GAMBLE COMPANY (US) 2006-08-30 EP disclosed
CN-1713887-A Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients PROCTER & GAMBLE (US) 2005-12-28 CN disclosed
EP-1562541-A1 CLEAR, STABLE, DRY-AND-NON-STICKY ANTIPERSPIRANT HAVING A SELECT GROUP OF POLAR SILICONE EMOLLIENTS THE PROCTER & GAMBLE COMPANY (US) 2005-08-17 EP disclosed
CN-1652984-A Low combustion aerosol product in plastic package having a reduced fire hazard classification PROCTER & GAMBLE (US) 2005-08-10 CN disclosed
CN-1652745-A Underarm product in a metered-dose and package PROCTER & GAMBLE (US) 2005-08-10 CN disclosed
US-20050123494-A1 Antiperspirant composition and applicator therefor PROCTER & GAMBLE COMPANY, THE 2005-06-09 US disclosed
WO-2005048966-A1 ANTIPERSPIRANT COMPOSITION AND APPLICATOR THEREFOR THE PROCTER & GAMBLE COMPANY (US) 2005-06-02 WO disclosed
EP-1506123-A1 LOW COMBUSTION AEROSOL PRODUCT IN PLASTIC PACKAGE HAVING A REDUCED FIRE HAZARD CLASSIFICATION THE PROCTER & GAMBLE COMPANY (US) 2005-02-16 EP disclosed
EP-1503728-A1 UNDERARM PRODUCT IN A METERED-DOSE PACKAGE THE PROCTER & GAMBLE COMPANY (US) 2005-02-09 EP disclosed
US-20040247546-A1 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients THE PROCTER & GAMBLE COMPANY 2004-12-09 US disclosed
US-6783027-B2 Metered-dose underarm product and package THE PROCTER & GAMBLE COMPANY 2004-08-31 US disclosed
CN-1509161-A Stable pressurized antiperspirant composition coutaining dimethylether propellant and low polarity solvent 2004-06-30 CN disclosed
WO-2004047786-A1 CLEAR, STABLE, DRY-AND-NON-STICKY ANTIPERSPIRANT HAVING A SELECT GROUP OF POLAR SILICONE EMOLLIENTS THE PROCTER & GAMBLE COMPANY (US) 2004-06-10 WO disclosed
CN-1479608-A Single-phase antiperspirant compositions containin solubilized antiperspirant active and volutile polysiloxane 2004-03-03 CN disclosed
EP-1390005-A2 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A POLYOL THE PROCTER & GAMBLE COMPANY (US) 2004-02-25 EP disclosed
WO-2003097485-A1 LOW COMBUSTION AEROSOL PRODUCT IN PLASTIC PACKAGE HAVING A REDUCED FIRE HAZARD CLASSIFICATION THE PROCTER & GAMBLE COMPANY (US) 2003-11-27 WO disclosed
WO-2003097002-A1 UNDERARM PRODUCT IN A METERED-DOSE PACKAGE THE PROCTER & GAMBLE COMPANY (US) 2003-11-27 WO disclosed
US-20030213818-A1 Metered-dose underarm product and package PROCTER & GAMBLE COMPANY, THE 2003-11-20 US disclosed
US-20030215399-A1 Low combustion aerosol products in plastic packages having a reduced fire hazard classification that subsequently reduces storage costs THE PROCTER & GAMBLE COMPANY 2003-11-20 US disclosed
EP-1343463-A2 SINGLE-PHASE ANTIPERSPIRANT COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE AND VOLATILE SILICONE The Procter & Gamble Company (US) 2003-09-17 EP disclosed
US-6555099-B2 For controlling malodor and perspiration; stability, low residue, cosmetics THE PROCTER & GAMBLE COMPANY 2003-04-29 US disclosed
US-6524562-B2 Low residue performance, enhanced stability; cosmetics THE PROCTER & GAMBLE COMPANY 2003-02-25 US disclosed
US-20030026773-A1 Anhydrous liquid antiperspirant emulsions THE PROCTER & GAMBLE COMPANY 2003-02-06 US disclosed
WO-2003002083-A2 ANHYDROUS LIQUID ANTIPERSPIRANT EMULSIONS THE PROCTER & GAMBLE COMPANY (US) 2003-01-09 WO disclosed
WO-2003002082-A1 PRESSURIZED ANHYDROUS ANTIPERSPIRANT EMULSIONS THE PROCTER & GAMBLE COMPANY (US) 2003-01-09 WO disclosed
US-20030007935-A1 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A LOW POLARITY SOLVENT THE PROCTER & GAMBLE COMPANY 2003-01-09 US disclosed
WO-2002094327-A2 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A POLYOL THE PROCTER & GAMBLE COMPANY (US) 2002-11-28 WO disclosed
US-6485715-B1 Stable pressurized antiperspirant compositions containing dimethylether propellant and a low polarity solvent THE PROCTOR & GAMBLE COMPANY 2002-11-26 US disclosed
US-20020110532-A1 Single-phase antiperspirant compositions containing solubilized antiperspirant active and volatile silicone PROCTER & GAMBLE COMPANY, THE 2002-08-15 US disclosed
US-20020106340-A1 Single-phase antiperspirant compositions containing solubilized antiperspirant active and silicone elastomer PROCTER & GAMBLE COMPANY, THE 2002-08-08 US disclosed
US-6416750-B1 MIXING ALUMINUM CHLOROHYDRATE, WATER, AND DIOL SOLVENT, SPRAY DRYING TO FORM POWDER, AND DISSOLVING INTO 1,2-DIOL SOLVENT (1,2-HEXANEDIOL); INCREASED FORMULATION FLEXIBILITY; LESS ENERGY INTENSIVE PROCESS SOMERVILLE TECHNOLOGY GROUP, INC. 2002-07-09 US disclosed
WO-2002047621-A2 SINGLE-PHASE ANTIPERSPIRANT COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE AND VOLATILE SILICONE THE PROCTER & GAMBLE COMPANY (US) 2002-06-20 WO disclosed
WO-2002047639-A2 SINGLE-PHASE ANTIPERSPIRANT COMPOSITIONS CONTAINING SILICONE ELASTOMER THE PROCTER & GAMBLE COMPANY (US) 2002-06-20 WO disclosed
US-6399049-B1 LIQUID 1,2-HYDROXYALKYL AMIDE, ESTER, ETHER, SILICONE OR ALKYL COMPOUND CARRIERS; NONIRRITATING; THE PROCTER & GAMBLE COMPANY 2002-06-04 US disclosed
EP-1206238-A2 COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP disclosed
EP-1206237-A1 COMPOSITIONS CONTAINING SOLUBILIZED, ACID-ENHANCED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP disclosed
WO-2001013872-A1 COMPOSITIONS CONTAINING SOLUBILIZED, ACID-ENHANCED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO disclosed
WO-2001013869-A2 COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO disclosed
US-6126928-A Compositions containing solubilized, acid-enhanced antiperspirant active THE PROCTER & GAMBLE COMPANY (US) 2000-10-03 US disclosed
US-6126928-A Compositions containing solubilized, acid-enhanced antiperspirant active THE PROCTER & GAMBLE COMPANY (US) 2000-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050123494-A1 Antiperspirant composition and applicator therefor CUTA, GPR27, OR51E2 LMNA 4008/4885ALDH1A1 1274/4885TDP1 848/4885
US-20030007935-A1 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A LOW POLARITY SOLVENT CDIPT, SIGMAR1, PHOSPHO1 LMNA 2490/4885ALDH1A1 2734/4885TDP1 2105/4885
US-20030215399-A1 Low combustion aerosol products in plastic packages having a reduced fire hazard classification that subsequently reduces storage costs ATP6V1H, ATP6V1G1, ATP6AP1 LMNA 3969/4885ALDH1A1 390/4885TDP1 1362/4885
US-20120269748-A1 Thickening Or Gelling Agent For Oily Raw Materials CUTA, PLOD3, FSCN1 LMNA 661/4885ALDH1A1 731/4885TDP1 2276/4885
US-20020106340-A1 Single-phase antiperspirant compositions containing solubilized antiperspirant active and silicone elastomer DDT, PON1, HDHD5 LMNA 2984/4885ALDH1A1 2575/4885TDP1 166/4885
US-20120269875-A1 Novel Co-Modified Organopolysiloxane IDUA, HPSE, DDOST LMNA 1338/4885ALDH1A1 2312/4885TDP1 3714/4885
US-20040247546-A1 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients SIGMAR1, SPTAN1, ELOVL1 LMNA 3000/4885ALDH1A1 4594/4885TDP1 1974/4885
US-20030026773-A1 Anhydrous liquid antiperspirant emulsions CUTA, NONO, SIGMAR1 LMNA 3835/4885ALDH1A1 1810/4885TDP1 835/4885
US-20020110532-A1 Single-phase antiperspirant compositions containing solubilized antiperspirant active and volatile silicone CUTA, PSPH, SFN LMNA 2437/4885ALDH1A1 3097/4885TDP1 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.