SCHEMBL3301693

SCHEMBL3301693

CCCCOc1ccc(CC)cc1[SiH](O[SiH](c1cc(CC)ccc1OCCCC)c1cc(CC)ccc1OCCCC)c1cc(CC)ccc1OCCCC

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
BACE1 P56817 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CNR2 P34972 3/20 0.38
ATM Q13315 1/20 0.38
TLR8 Q9NR97 1/20 0.38
CSNK2A1 P68400 2/20 0.37
BIRC5 O15392 1/20 0.36
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3300336 0.89 GLA (0.39) GLASMN1; SMN2BACE1CYP1A2CYP2C9
SCHEMBL3293995 0.84 CALM1 (0.38) SMN1; SMN2CYP1A2CYP2C9
SCHEMBL3295598 0.83 LTA4H (0.44) GLASMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL3294303 0.81 KDM4E (0.45) GLASMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL13462924 0.80 BIRC5 (0.51) GLASMN1; SMN2BACE1CYP1A2CYP2C9
SCHEMBL3298757 0.79 PTGS2 (0.48) SMN1; SMN2CYP1A2ATM
SCHEMBL3298753 0.78 KDM4E (0.44) SMN1; SMN2CYP1A2CYP2C9CYP2C19TLR8
SCHEMBL3296160 0.77 CYP1A2 (0.55) CYP1A2CYP2C9CYP2C19ATMTLR8
SCHEMBL3299743 0.77 CYP1A2 (0.40) GLASMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL10873504 0.76 S1PR2 (0.49) GLASMN1; SMN2CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 GLA 304/4885SMN1; SMN2 1035/4885BACE1 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.