Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304592 | 1.00 | ESR1 (0.56) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL3303839 | 1.00 | ESR1 (0.56) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL30504752 | 0.85 | ALDH1A1 (0.47) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL5596220 | 0.85 | ALDH1A1 (0.47) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL3962146 | 0.83 | ESR1 (0.54) | ESR1ESR2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL5810167 | 0.83 | ESR1 (0.54) | ESR1ESR2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL2551265 | 0.76 | TDP1 (0.52) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL5596874 | 0.76 | TDP1 (0.52) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL30759711 | 0.76 | TDP1 (0.52) | ESR1ESR2ALDH1A1TDP1CA2 | |
| SCHEMBL3632062 | 0.76 | ESR1 (0.48) | ESR1ESR2TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-10-26 | — | — | US | disclosed |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PHOSPHOENIX SARL (FR) | 2010-04-22 | — | — | US | disclosed |
| EP-1899358-A2 | NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS | Phosphoenix SARL (FR) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006136695-A2 | NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS | PHOSPHOENIX SARL (FR) | 2006-12-28 | — | — | WO | disclosed |
| EP-0128596-B1 | ETHYLENE OLIGOMERIZATION PROCESS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-05-20 | — | — | EP | disclosed |
| US-4503279-A | NICKEL CATALYST FORMED IN SITU | SHELL OIL COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| US-4503280-A | NICKEL COMPLEX CATALYST | SHELL OIL COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0128597-A2 | Ethylene oligomerization process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-12-19 | — | — | EP | disclosed |
| EP-0128596-A2 | Ethylene oligomerization process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-12-19 | — | — | EP | disclosed |
| US-4472522-A | SUING POLYMERIZATION CATALYST COMPOSITION OF NICKEL SALT, BORON HYDRIDE REDUCING AGENT, AND O-DIHYDROCARBYLPHOSPHINOPHENYL ALCOHOL OR ETHER | SHELL OIL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| US-4472525-A | POLYMERIZATION CATALYST CONSISTING OF NICKEL COMPOUND AND O-DIHYDROCARBYLPHOSPHINOPHENYL ALCOHOL ETHER | SHELL OIL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PNP, NANP, PHOSPHO1 | ESR1 1016/4885ESR2 1023/4885ALDH1A1 834/4885 |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | ESR1 3850/4885ESR2 4668/4885ALDH1A1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.