Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.47 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.79 |
| ▸ | NPC1 | O15118 | 6/20 | 0.79 |
| ▸ | RAB9A | P51151 | 6/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | RAD52 | P43351 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL636714 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| Hydrochloric Acid SCHEMBL444300 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| Hydrochloric Acid SCHEMBL30980102 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| Hydrochloric Acid SCHEMBL635996 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| Hydrochloric Acid SCHEMBL330172 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| Hydrochloric Acid SCHEMBL2530562 | 1.00 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| SCHEMBL627771 | 0.98 | SMN1; SMN2 (0.81) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| SCHEMBL4070988 | 0.98 | SMN1; SMN2 (0.81) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| Hydrochloric Acid SCHEMBL9358066 | 0.98 | SMN1; SMN2 (0.75) | SMN1; SMN2NPC1RAB9APOLBHTT | |
| SCHEMBL627732 | 0.98 | SMN1; SMN2 (0.81) | SMN1; SMN2NPC1RAB9APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | claimed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | claimed |
| US-20160186232-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2016-06-30 | — | — | US | claimed |
| EP-3031914-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING SAME, AGENT FOR IMPROVING SURFACTANT-RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING SAME | Kikkoman Corporation (JP) | 2016-06-15 | — | — | EP | claimed |
| US-4286038-A | DRY DEVELOPERS, CARBON BLACK, A STYRENE POLYMER AND A FLUOROPOLYMER COATED STEEL CORE | XEROX CORPORATION (US) | 1981-08-25 | — | — | US | claimed |
| US-20260022412-A1 | METHOD AND KIT FOR DETECTING MICROORGANISM OR CELL, DETECTING MICROORGANISM RELATED SUBSTANCE OR CELL RELATED SUBSTANCE | KIKKOMAN CORPORATION (JP) | 2026-01-22 | — | — | US | disclosed |
| EP-4560025-A1 | METHOD AND KIT FOR DETECTING MICROORGANISM OR CELL, OR DETECTING MICROORGANISM RELATED SUBSTANCE OR CELL RELATED SUBSTANCE | Kikkoman Corporation (JP) | 2025-05-28 | — | — | EP | disclosed |
| CN-111398605-B | Glycosylated hemoglobin measurement composition | 龟甲万株式会社 | 2024-04-05 | — | — | CN | disclosed |
| WO-2024019165-A1 | METHOD AND KIT FOR DETECTING MICROORGANISM OR CELL, OR DETECTING MICROORGANISM RELATED SUBSTANCE OR CELL RELATED SUBSTANCE | キッコーマン株式会社 | 2024-01-25 | — | — | WO | disclosed |
| WO-2024019166-A1 | METHOD AND KIT FOR DETECTING MICROORGANISM, CELL, MICROORGANISM-RELATED SUBSTANCE OR CELL-RELATED SUBSTANCE IN SOLUTION | キッコーマン株式会社 | 2024-01-25 | — | — | WO | disclosed |
| EP-3061819-B1 | HEMOGLOBIN A1c MEASUREMENT METHOD AND MEASUREMENT KIT | KIKKOMAN CORP (JP) | 2023-05-24 | — | — | EP | disclosed |
| EP-3279323-B1 | AMADORIASE HAVING IMPROVED SPECIFIC ACTIVITY | KIKKOMAN CORP (JP) | 2023-03-08 | — | — | EP | disclosed |
| EP-1319966-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-1316819-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-0819737-B1 | Aqueous pigment ink composition | ORIENT CHEMICAL IND (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5861447-A | OXIDIZED CARBON BLACK USING HYPOHALOUS ACID AND A WATER SOLUBLE CATIONIC POLYMER | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0819737-A2 | Aqueous pigment ink composition | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-21 | — | — | EP | disclosed |
| EP-0468404-B1 | Process for preparing di-tert.-butyl dicarbonate | SUMITOMO CHEMICAL CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5151542-A | Reacting an alkali metal tert-butyl carbonate with methanesulfonyl chloride | SUMITOMO CHEMICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0468404-A2 | Process for preparing di-tert.-butyl dicarbonate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022412-A1 | METHOD AND KIT FOR DETECTING MICROORGANISM OR CELL, DETECTING MICROORGANISM RELATED SUBSTANCE OR CELL RELATED SUBSTANCE | P2RY6, TK1, P2RX6 | CHRM2 821/4885CHRM1 815/4885ACHE 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.