Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305886 | 0.94 | CHRM2 (0.55) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL24061764 | 0.81 | CHRM2 (0.60) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL5542951 | 0.80 | TSHR (0.47) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL18664540 | 0.80 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL3305905 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL5548182 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HTTKDM4EKMT2A | |
| SCHEMBL7444665 | 0.78 | CHRM2 (0.66) | ALDH1A1KDM4EMEN1KMT2ACHRM2 | |
| SCHEMBL7638550 | 0.78 | CHRM2 (0.55) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL5537784 | 0.77 | HDAC4 (0.44) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL7287770 | 0.76 | CHRM2 (0.62) | ALDH1A1SMN1; SMN2HTTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | SHIONOGI & CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2128134-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | Shionogi&Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | MMP13, MMP3, MMP26 | ALDH1A1 469/4885SMN1; SMN2 1299/4885HTT 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.