Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232281 | 0.83 | PLA2G7 (0.39) | PLA2G7HPGDTSHRCSF1R | |
| SCHEMBL12471409 | 0.78 | ALOX15 (0.37) | HPGDTSHRGRM5 | |
| SCHEMBL5149265 | 0.73 | HPGD (0.34) | PLA2G7HPGDTSHRGRM5DPP4 | |
| SCHEMBL29868298 | 0.72 | PLA2G7 (0.37) | PLA2G7HPGDTSHR | |
| SCHEMBL20555017 | 0.72 | PLA2G7 (0.39) | PLA2G7DPP4 | |
| SCHEMBL29868565 | 0.72 | PLA2G7 (0.39) | PLA2G7DPP4 | |
| SCHEMBL661007 | 0.72 | PLA2G7 (0.37) | PLA2G7HPGDTSHR | |
| SCHEMBL660731 | 0.72 | PLA2G7 (0.39) | PLA2G7DPP4 | |
| SCHEMBL29868300 | 0.72 | PLA2G7 (0.37) | PLA2G7HPGDTSHR | |
| SCHEMBL2948183 | 0.71 | ALDH1A1 (0.37) | PLA2G7HPGDTSHRGRM5CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099735-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099735-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | BACE2, RAB2A, VAMP8 | PLA2G7 705/4885HPGD 3278/4885TSHR 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.