SCHEMBL330663

SCHEMBL330663

CC(S)c1ccccc1C(C)S

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.43
GABRB2 P47870 2/20 0.43
TSHR P16473 3/20 0.39
PTGS1 P23219 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
FAAH O00519 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
GABRB1 P18505 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
HTR2B P41595 1/20 0.39
GABRA2 P47869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18856680 0.91 GABRA1 (0.50) GABRA1GABRB2TSHRPTGS1GABRG2
SCHEMBL13242010 0.85 GABRA1 (0.39) GABRA1GABRB2TSHRPTGS1GABRG2
SCHEMBL22802642 0.83 ESR1 (0.52) GABRA1GABRB2TSHRCYP3A4CA1
SCHEMBL1962794 0.83 ESR1 (0.52) GABRA1GABRB2TSHRCYP3A4CA1
SCHEMBL24988976 0.81 ACHE (0.40) GABRA1GABRB2CYP3A4HIF1AACHE
SCHEMBL6535448 0.81 GABRA1 (0.65) GABRA1GABRB2TSHRPTGS1GABRG2
SCHEMBL8468418 0.81 CYP3A4 (0.43) GABRA1GABRB2TSHRPTGS1GABRG2
SCHEMBL21216509 0.81 ACHE (0.40) GABRA1GABRB2CYP3A4HIF1AACHE
SCHEMBL2762643 0.81 GABRA1 (0.36) GABRA1GABRB2TSHRPTGS1GABRG2
SCHEMBL17161261 0.81 GABRA1 (0.36) GABRA1GABRB2TSHRPTGS1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US claimed
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
US-11548971-B2 Method for producing a resin lens from a polyisocyanate and release agent at reduced pressure YIFENG NEW MATERIALS CO., LTD. (CN) 2023-01-10 US claimed
US-11402755-B2 Chemically amplified positive-type photosensitive resin composition, method for manufacturing substrate with template, and method for manufacturing plated article TOKYO OHKA KOGYO CO., LTD. (JP) 2022-08-02 US claimed
US-20210221940-A1 RESIN LENS AND METHOD FOR PRODUCING THE SAME SHANDONG EFIRM BIOCHEMISTRY AND ENVIRONMENTAL PROTECTION CO., LTD. (CN) 2021-07-22 US claimed
CN-108546325-B A kind of resin lens and preparation method thereof 山东益丰生化环保股份有限公司 2019-07-09 CN claimed
CN-108546325-A A kind of resin lens and preparation method thereof 山东益丰生化环保股份有限公司 2018-09-18 CN claimed
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
US-6391433-B1 None US disclosed
WO-2026105643-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
WO-2026105644-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-05-12 US disclosed
EP-4725987-A2 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS TECHNICAL FIELD Mitsui Chemicals, Inc. (JP) 2026-04-15 EP disclosed
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof COVESTRO DEUTSCHLAND AG (DE) 2026-03-10 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom RAD51, SMURF1, SMARCA1 GABRA1 2011/4885GABRB2 2947/4885TSHR 3022/4885
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof RB1, ALDH1A2, IDH3A GABRA1 3359/4885GABRB2 3073/4885TSHR 4771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.