Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307658 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL3305491 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AKDM4ECYP2D6 | |
| SCHEMBL3305497 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AKDM4ECYP2D6 | |
| SCHEMBL14864458 | 0.78 | HTR6 (0.50) | SMN1; SMN2CYP1A2CYP1A1CYP1B1ALOX5 | |
| SCHEMBL13394314 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL1850926 | 0.73 | NFE2L2 (0.50) | MAPK1NFE2L2MAPTMAOBALDH1A1 | |
| SCHEMBL1850928 | 0.73 | NFE2L2 (0.50) | MAPK1NFE2L2MAPTMAOBALDH1A1 | |
| SCHEMBL3306489 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ACYP3A4HPGD | |
| SCHEMBL3306493 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ACYP3A4HPGD | |
| SCHEMBL13394312 | 0.67 | NFE2L2 (0.51) | SMN1; SMN2KDM4EALOX5GAANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420052-B2 | Imaging agents useful for identifying AD pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | APP, APBA1, PYGB | SMN1; SMN2 69/4885NPC1 719/4885RAB9A 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.