Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890213 | 0.90 | CA12 (0.55) | CA12CA7CA14CA1CA2 | |
| SCHEMBL14890057 | 0.87 | NPC1 (0.48) | CA12CA7CA14CA1CA2 | |
| SCHEMBL2575691 | 0.86 | CA12 (0.63) | CA12CA7CA14CA1CA2 | |
| SCHEMBL2554893 | 0.86 | PKM (0.47) | CA12CA7CA14CA1CA2 | |
| SCHEMBL14890086 | 0.86 | CA12 (0.45) | CA12CA7CA14CA1CA2 | |
| SCHEMBL2575564 | 0.85 | CA12 (0.54) | CA12CA7CA14CA1CA2 | |
| SCHEMBL14889950 | 0.85 | CA12 (0.50) | CA12CA7CA14CA1CA2 | |
| SCHEMBL2575983 | 0.85 | CA12 (0.51) | CA12CA7CA14CA1CA2 | |
| SCHEMBL30471759 | 0.83 | CA12 (0.53) | CA12CA7CA14CA1CA2 | |
| SCHEMBL1787681 | 0.82 | CA12 (0.49) | CA12CA7CA14CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| CN-103038213-A | Process for the preparation of pyrrolines from gamma-nitroketones, use of the gamma-nitroketones as pesticidal agents | BAYER CROPSCIENCE AG | 2013-04-10 | — | — | CN | disclosed |
| EP-2558444-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | Bayer Intellectual Property GmbH (DE) | 2013-02-20 | — | — | EP | disclosed |
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011128299-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011128299-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109757-A1 | PROCESS FOR THE PREPARATION OF PYRROLINES FROM GAMMA-NITROKETONES. USE OF THE GAMMA-NITROKETONES AS PESTICIDAL AGENTS | NOS2, PDXK, GSTK1 | CA12 3988/4885CA7 1037/4885CA14 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.