Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | XBP1 | P17861 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Grinimibine SCHEMBL4132680 | 0.81 | MAPT (1.00) | MAPTPOLBXBP1NPC1RAB9A | |
| SCHEMBL29502491 | 0.68 | MAPT (0.72) | MAPTPOLBXBP1NPC1RAB9A | |
| SCHEMBL30929792 | 0.66 | MAPT (0.69) | MAPTPOLBXBP1NPC1RAB9A | |
| Koenimbine SCHEMBL29581663 | 0.66 | MAPT (0.69) | MAPTPOLBXBP1NPC1RAB9A | |
| SCHEMBL30929796 | 0.66 | MAPT (0.65) | MAPTPOLBXBP1NPC1RAB9A | |
| Mahanimbine SCHEMBL18488200 | 0.63 | MAPT (1.00) | MAPTPOLBXBP1NPC1RAB9A | |
| Mahanimbine SCHEMBL2991765 | 0.63 | MAPT (1.00) | MAPTPOLBXBP1NPC1RAB9A | |
| Mahanimbine SCHEMBL18488203 | 0.63 | MAPT (1.00) | MAPTPOLBXBP1NPC1RAB9A | |
| SCHEMBL31324179 | 0.63 | MAPT (0.60) | MAPTPOLBXBP1NPC1RAB9A | |
| SCHEMBL6052168 | 0.62 | MAPT (0.43) | MAPTPOLBXBP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100098788-A1 | Extracts of Curcuma and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2010-04-22 | — | — | US | disclosed |