SCHEMBL331246

SCHEMBL331246

O=C(CS)OC1CCC(OC(=O)CS)CC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NAAA Q02083 2/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 2/20 0.37
CYP19A1 P11511 6/20 0.37
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
EPHX1 P07099 2/20 0.33
SERPINE1 P05121 1/20 0.33
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15921260 1.00
SCHEMBL4679989 0.90 NAAA (0.50) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL11600264 0.89 CYP19A1 (0.50) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL1405464 0.88 CYP2C19 (0.53) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL5933034 0.85 CYP19A1 (0.53) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL25475321 0.84 CPN1 (0.40) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL9809370 0.84 APOBEC3A (0.56) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL11546661 0.83 NAAA (0.49) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL11546677 0.83 NAAA (0.49) TSHRHSD17B10NAAACYP2C19HTT
SCHEMBL11547705 0.81 NAAA (0.50) TSHRHSD17B10NAAACYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2921511-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL AND MANUFACTURING METHOD FOR SAME MITSUI CHEMICALS INC (JP) 2017-11-01 EP claimed
US-9778397-B2 Polymerizable composition, optical material, and manufacturing method of the same MITSUI CHEMICALS, INC. (JP) 2017-10-03 US claimed
US-20150331147-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, AND MANUFACTURING METHOD OF THE SAME MITSUI CHEMICALS, INC. (JP) 2015-11-19 US claimed
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-05-12 US disclosed
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof COVESTRO DEUTSCHLAND AG (DE) 2026-03-10 US disclosed
US-20250382514-A1 CURABLE ADHESIVE COMPOSITION COMPRISING MALEIMIDE AND THIOL HENKEL AG & CO KGAA (DE) 2025-12-18 US disclosed
EP-3841141-B1 A COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF COVESTRO DEUTSCHLAND AG (DE) 2025-01-01 EP disclosed
EP-3601405-B1 GENERATION OF POLYISOCYANURATE LAYERS THROUGH SEPARATE APPLICATION OF ISOCYANATE COMPONENTS AND CATALYSTS COVESTRO DEUTSCHLAND AG (DE) 2024-08-28 EP disclosed
US-11965054-B2 Storage-stable pigmented isocyanate group-containing formulations with isocyanate group-containing grinding resin and use thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
US-11965108-B2 Composition, preparation method and application thereof COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
US-20240085791-A1 COLORED PHOTOSENSITIVE RESIN COMPOSITION AND MUTILAYER CURED FILM PREPARED THEREFROM ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2024-03-14 US disclosed
EP-1925629-A1 POLYTHIOURETHANE-BASED POLYMERIZABLE COMPOSITION AND OPTICAL RESIN OBTAINED FROM THE SAME Mitsui Chemicals, Inc. (JP) 2008-05-28 EP disclosed
EP-1923415-A1 POLYURETHANE/THIOURETHANE-BASED OPTICAL RESIN AND PROCESS FOR PRODUCING THE SAME Mitsui Chemicals, Inc. (JP) 2008-05-21 EP disclosed
EP-1878758-A1 POLYTHIOURETHANE POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCING OPTICAL RESIN BY USING SAME Mitsui Chemicals, Inc. (JP) 2008-01-16 EP disclosed
US-20070203318-A1 Polyurethanes Polymerizable Composition And Method For Producing Optical Resin Of The Same MITSUI CHEMICALS, INC. (JP) 2007-08-30 US disclosed
EP-1746118-A1 POLYURETHANE POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCING OPTICAL RESIN COMPOSED OF SAME Mitsui Chemicals, Inc. (JP) 2007-01-24 EP disclosed
US-4985485-A HYDROTALCITE RHONE-POULENC CHIMIE (FR) 1991-01-15 US disclosed
US-4921896-A RED PHOSPHORUS, LANTHANIDE, TALC, ZINC SULFIDE OR ZINC OXIDE RHONE-POULENC CHIMIE (FR) 1990-05-01 US disclosed
US-4612339-A YTTRIUM OR LANTHANDIDE COMPOUND; AMMONIUM, ALKALI OR ALKALINE EARTH METAL HALIDE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-09-16 US disclosed
US-4559372-A ADDITIVES OF RED PHOSPHORUS AND A LANTHANIDE AND/OR YTTRIUM COMPOUND; NONTOXIC;ARC TRACKING RESISTANCE RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1985-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom RAD51, SMURF1, SMARCA1 TSHR 3022/4885HSD17B10 4667/4885NAAA 4817/4885
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof RB1, ALDH1A2, IDH3A TSHR 4771/4885HSD17B10 1234/4885NAAA 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.