Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337300 | 0.90 | ALDH1A1 (0.43) | PGRKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL1472540 | 0.90 | ALDH1A1 (0.43) | PGRKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL18943971 | 0.82 | PGR (0.40) | PGRGFRA3RETALDH1A1TDP1 | |
| SCHEMBL22727906 | 0.81 | KDM4E (0.41) | KDM4EPTGS2RAB9AALDH1A1MEN1 | |
| SCHEMBL25367772 | 0.79 | ALDH1A1 (0.41) | KDM4EPTGS2RAB9AALDH1A1MEN1 | |
| SCHEMBL13390906 | 0.79 | ALDH1A1 (0.38) | KDM4EPTGS2RAB9AALDH1A1MEN1 | |
| SCHEMBL8255368 | 0.79 | ALDH1A1 (0.38) | KDM4EPTGS2RAB9AALDH1A1MEN1 | |
| SCHEMBL25365364 | 0.78 | ALDH1A1 (0.42) | KDM4EPTGS2RAB9AALDH1A1MEN1 | |
| SCHEMBL11720441 | 0.76 | PGR (0.42) | PGRGFRA3RETPYGLPTGER2 | |
| SCHEMBL25367287 | 0.75 | PPARD (0.40) | ALDH1A1MEN1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |
| WO-2009038411-A2 | BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |