Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13390906 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL2560483 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL12932008 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL20283375 | 0.86 | ACHE (0.44) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL22516886 | 0.83 | XDH (0.41) | ALDH1A1MAPTANPEPACHEKDM4E | |
| SCHEMBL22727908 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL25367772 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL33126 | 0.79 | PGR (0.40) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL22516927 | 0.78 | ESR1 (0.51) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL22516616 | 0.78 | ESR1 (0.41) | ANPEPACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116157-A9 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS INC (US) | 2007-03-01 | — | — | WO | disclosed |