SCHEMBL25367287

SCHEMBL25367287

CCC1CCc2cc(C=O)ccc21

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 11/20 0.40
PPARA Q07869 2/20 0.39
FFAR1 O14842 1/20 0.39
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
DRD2 P14416 1/20 0.35
DRD1 P21728 1/20 0.35
DRD4 P21917 1/20 0.35
DRD5 P21918 1/20 0.35
DRD3 P35462 1/20 0.35
ALDH1A3 P47895 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25368354 0.88 PPARD (0.39) PPARDPPARAFFAR1ESR1ESR2
SCHEMBL25368248 0.87 MTNR1A (0.40) ESR1ESR2
SCHEMBL25366773 0.85 XDH (0.38) PPARDPPARAFFAR1ESR1ESR2
SCHEMBL25367772 0.78 ALDH1A1 (0.41) ESR1ESR2MEN1ALDH1A1GAA
SCHEMBL25369795 0.75 MTNR1A (0.44)
SCHEMBL25366778 0.75 PPARD (0.39) PPARDPPARAFFAR1ESR1ESR2
SCHEMBL8255368 0.75 ALDH1A1 (0.38) MEN1ALDH1A1GAAMAPTHPGD
SCHEMBL13390906 0.75 ALDH1A1 (0.38) MEN1ALDH1A1GAAMAPTHPGD
SCHEMBL13958835 0.75 ESR1 (0.66) ESR1ESR2MEN1ALDH1A1GAA
SCHEMBL13948427 0.75 HTR2A (0.49) PPARDESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583809-B2 Process for preparing indene acryladehyde derivatives FIRMENICH SA (CH) 2026-03-24 US disclosed
EP-4149913-B1 PROCESS FOR PREPARING INDENE ACRYLADEHYDE DERIVATIVES FIRMENICH & CIE (CH) 2024-07-17 EP disclosed
US-20230271911-A1 PROCESS FOR PREPARING INDENE ACRYLADEHYDE DERIVATIVES FIRMENICH SA (CH) 2023-08-31 US disclosed
CN-115768740-A Process for preparing indene acrolein derivative 弗门尼舍有限公司 2023-03-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583809-B2 Process for preparing indene acryladehyde derivatives CBR1, CYP2E1, CYP2C8 PPARD 2448/4885PPARA 2699/4885FFAR1 232/4885
US-20230271911-A1 PROCESS FOR PREPARING INDENE ACRYLADEHYDE DERIVATIVES HPD, IMPDH1, IMPDH2 PPARD 1736/4885PPARA 2775/4885FFAR1 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.