Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | NR0B2 | Q15466 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311930 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL3309247 | 0.81 | HDAC11 (0.43) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL13330416 | 0.80 | SIGMAR1 (0.42) | MEN1KMT2AHTR2CGRIN1GRIN2A | |
| SCHEMBL13330411 | 0.75 | CNR2 (0.40) | ALDH1A1MEN1KMT2ATDP1PTPN11 | |
| SCHEMBL3316211 | 0.75 | TSHR (0.30) | PTPN11NR0B2TSHR | |
| SCHEMBL3179232 | 0.72 | MEN1 (0.45) | ALDH1A1MEN1KMT2AGRIN1GRIN2A | |
| SCHEMBL4573426 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL18184323 | 0.69 | HDAC6 (0.46) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL18170344 | 0.69 | HDAC6 (0.46) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL18170343 | 0.69 | HDAC6 (0.46) | ALDH1A1MEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113816-A1 | METHOD FOR PREPARTION OF SUBSTITUTED ADAMANTYLARYMAGNESIUM HALIDES | JSC GRINDEKS (LV) | 2010-05-06 | — | — | US | disclosed |
| EP-2129679-A2 | A METHOD FOR PREPARATION OF SUBSTITUTED ADAMANTYLARYLMAGNESIUM HALIDES | Grindeks, a joint stock company (LV) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008080993-A2 | A METHOD FOR PREPARATION OF SUBSTITUTED ADAMANTYLARYLMAGNESIUM HALIDES | KALVINSH IVARS (LV) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113816-A1 | METHOD FOR PREPARTION OF SUBSTITUTED ADAMANTYLARYMAGNESIUM HALIDES | AGL, MACROD1, MACROD2 | ALDH1A1 1779/4885MEN1 294/4885KMT2A 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.