Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18170343 | 1.00 | HDAC6 (0.46) | HDAC6HDAC8GRIN1GRIN2AKDM1A | |
| SCHEMBL18184323 | 1.00 | HDAC6 (0.46) | HDAC6HDAC8GRIN1GRIN2AKDM1A | |
| SCHEMBL18166480 | 1.00 | HDAC6 (0.46) | HDAC6HDAC8GRIN1GRIN2AKDM1A | |
| SCHEMBL18179943 | 0.84 | HDAC6 (0.49) | HDAC6HDAC8GRIN1GRIN2AGRIN2D | |
| SCHEMBL20959894 | 0.84 | MEN1 (0.50) | KDM1AMAOAMAOBKDM1BMEN1 | |
| SCHEMBL3359762 | 0.84 | MEN1 (0.50) | KDM1AMAOAMAOBKDM1BMEN1 | |
| Hydrochloric Acid SCHEMBL3363220 | 0.83 | MEN1 (0.52) | KDM1AMAOAMAOBKDM1BMEN1 | |
| SCHEMBL20959900 | 0.81 | MEN1 (0.47) | KDM1AMAOAMAOBKDM1BMEN1 | |
| SCHEMBL22353273 | 0.80 | KDM1A (0.40) | KDM1AMAOAMAOBKDM1BMEN1 | |
| SCHEMBL3311930 | 0.72 | ALDH1A1 (0.38) | HDAC6HDAC8GRIN1GRIN2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | claimed |
| US-20160310448-A1 | Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2016-10-27 | — | — | US | claimed |
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | disclosed |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-08-07 | — | — | US | disclosed |
| US-20160310448-A1 | Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | ADRA1A, ADRA1B, ADRA1D | HDAC6 4361/4885HDAC8 4222/4885GRIN1 1262/4885 |
| US-20160310448-A1 | Adamantane or Pinene Derivatives for Use in the Treatment of Chlamydiales Infections | ADRA1A, ADRA1B, ADRA1D | HDAC6 4267/4885HDAC8 4223/4885GRIN1 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.