Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337282 | 0.77 | TDP1 (0.40) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL13999989 | 0.73 | ALDH1A1 (0.51) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL8270843 | 0.71 | TDP1 (0.40) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL564506 | 0.70 | TDP1 (0.52) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL29595940 | 0.70 | TDP1 (0.52) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL3990674 | 0.70 | TDP1 (0.52) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL30110723 | 0.70 | TDP1 (0.52) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL1967460 | 0.69 | LMNA (0.42) | TDP1ALDH1A1CYP3A4GPR35MAPT | |
| SCHEMBL8698196 | 0.69 | TDP1 (0.50) | TDP1ATMALDH1A1CYP3A4HIF1A | |
| SCHEMBL429318 | 0.68 | TDP1 (0.40) | TDP1ATMALDH1A1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746999-B1 | 4-PHENYLAMINO-QUINAZOLIN-6-YL-AMIDES | WARNER LAMBERT CO (US) | 2011-11-16 | — | — | EP | disclosed |