SCHEMBL3313586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27726801	0.84	PTPN11 (0.55)	GAATSHRTP53PTPN11
	SCHEMBL2902590	0.82	FLT3 (0.66)	GAATSHRFLT3ALDH1A1KDM4E
	SCHEMBL8638210	0.81	GAA (0.57)	GAATSHRFLT3ALDH1A1KDM4E
	SCHEMBL8352125	0.81	KDM4E (0.56)	GAATSHRALDH1A1L3MBTL1KDM4E
	SCHEMBL11775703	0.81	ALDH1A1 (0.53)	GAAALDH1A1KDM4ETP53PTPN11
	SCHEMBL14573825	0.79	GAA (0.55)	GAATSHRFLT3ALDH1A1KDM4E
	SCHEMBL7635214	0.79	TSHR (0.57)	GAATSHRFLT3ALDH1A1L3MBTL1
	SCHEMBL18614861	0.79	GAA (0.70)	GAATSHRFLT3ALDH1A1KDM4E
	SCHEMBL27051430	0.79	GAA (0.51)	GAATSHRFLT3ALDH1A1KDM4E
	SCHEMBL5390124	0.79	GAA (0.53)	GAATSHRFLT3ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.