Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313789 | 0.92 | FAAH (0.46) | ALDH1A1SMN1; SMN2HPGDLMNAGAA | |
| SCHEMBL3316461 | 0.91 | L3MBTL1 (0.41) | LTA4HEPHX2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3317404 | 0.77 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2HPGDLIPE | |
| SCHEMBL3314829 | 0.77 | CCR3 (0.41) | LTA4HEPHX2ALDH1A1POLBLMNA | |
| SCHEMBL3317869 | 0.73 | HRH3 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL4716599 | 0.71 | GRM7 (0.40) | LTA4HEPHX2L3MBTL1ALDH1A1GAA | |
| SCHEMBL3316432 | 0.71 | KMT2A (0.47) | EPHX2L3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3318035 | 0.71 | FAAH (0.53) | LTA4HL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3007280 | 0.70 | SMN1; SMN2 (0.43) | LTA4HEPHX2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3316638 | 0.69 | GRM7 (0.43) | LMNAGRM7RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | VERNALIS (R&D) LIMITED (GB) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | CNR1, OPRL1, CHRNA10 | LTA4H 642/4885EPHX2 1305/4885L3MBTL1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.