Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 3/20 | 0.38 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313736 | 0.91 | LTA4H (0.44) | L3MBTL1SMN1; SMN2ALDH1A1LIPEHPGD | |
| SCHEMBL3313789 | 0.83 | FAAH (0.46) | SMN1; SMN2ALDH1A1HPGDMMP3 | |
| SCHEMBL3317404 | 0.82 | ALDH1A1 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1LIPEHPGD | |
| SCHEMBL3314829 | 0.77 | CCR3 (0.41) | ALDH1A1POLBLTA4HEPHX2MLNR | |
| SCHEMBL3017767 | 0.70 | TP53 (0.39) | SMN1; SMN2POLBLTA4HEPHX2BRS3 | |
| SCHEMBL3022615 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LTA4HMLNRROCK2 | |
| SCHEMBL3317018 | 0.68 | HTR1D (0.52) | — | |
| SCHEMBL3317869 | 0.67 | HRH3 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1HPGDCYP3A4 | |
| SCHEMBL3022442 | 0.66 | LIPG (0.41) | ALDH1A1LIPEMMP2MMP1MMP3 | |
| SCHEMBL30755036 | 0.66 | SMN1; SMN2 (0.56) | L3MBTL1SMN1; SMN2ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | VERNALIS (R&D) LIMITED (GB) | 2010-04-29 | — | — | US | disclosed |
| US-20100105755-A1 | SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | CNR1, OPRL1, CHRNA10 | L3MBTL1 861/4885SMN1; SMN2 784/4885ALDH1A1 1255/4885 |
| US-20100105755-A1 | SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR | DBH, SLC6A3, HTR5A | L3MBTL1 4498/4885SMN1; SMN2 2869/4885ALDH1A1 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.