Thioglycolic Acid

Thioglycolic Acid

SCHEMBL331396

CSSO.O=C(O)CS.O=C(O)CS

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.35
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.33
FOLH1 Q04609 1/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
RNPEP Q9H4A4 1/20 0.31
ACE P12821 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL18423900 1.00
Thioglycolic Acid SCHEMBL331620 0.88 FFAR3 (0.39) FFAR3TSHRHSD17B10FOLH1CYP2D6
Thioglycolic Acid SCHEMBL28080694 0.88
Mercaptopropionic Acid SCHEMBL18423384 0.81 ACE (0.48) FFAR3TSHRHSD17B10FOLH1ACE
Mercaptopropionic Acid SCHEMBL331074 0.81 ACE (0.48) FFAR3TSHRHSD17B10FOLH1ACE
Thioglycolic Acid SCHEMBL874629 0.77
Thioglycolic Acid SCHEMBL3079958 0.77
Thioglycolic Acid SCHEMBL9449577 0.77
Thioglycolic Acid SCHEMBL134322 0.77 LMNA (0.46) FFAR3TSHRHSD17B10FOLH1CYP2D6
Thioglycolic Acid SCHEMBL21017 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US claimed
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
US-6391433-B1 None US disclosed
WO-2026105643-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
WO-2026105644-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
EP-4725987-A2 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS TECHNICAL FIELD Mitsui Chemicals, Inc. (JP) 2026-04-15 EP disclosed
EP-4198069-B1 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITON, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS MITSUI CHEMICALS INC (JP) 2026-03-04 EP disclosed
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film ARTIENCE CO., LTD. (JP) 2026-01-27 US disclosed
EP-4674881-A2 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, RESIN, MOLDED BODY, OPTICAL ELEMENT AND LENS Mitsui Chemicals, Inc. (JP) 2026-01-07 EP disclosed
EP-3919584-B1 METHOD FOR PRODUCING POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2025-12-24 EP disclosed
EP-4151623-B1 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, RESIN, MOLDED BODY, OPTICAL ELEMENT AND LENS MITSUI CHEMICALS INC (JP) 2025-11-26 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film EPB41, ITGB4, ITGB5 FFAR3 1226/4885TSHR 657/4885HSD17B10 3658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.