Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM6A | O15550 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060128 | 0.79 | KDM4E (0.51) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL878561 | 0.78 | KDM4E (0.40) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL3319649 | 0.72 | APP (0.37) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9386569 | 0.71 | KDM4E (0.39) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL254514 | 0.65 | DUT (0.56) | UPP1 | |
| SCHEMBL24114956 | 0.65 | PNP (0.41) | HTTUPP1USP2PNPTSHR | |
| SCHEMBL10480769 | 0.65 | KDM4E (0.42) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL958138 | 0.64 | KDM4E (0.55) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL4754379 | 0.61 | KDM4E (0.46) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8129400 | 0.61 | KDM4E (0.44) | KDM4ETP53CYP2D6HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334320-B2 | Methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-12-18 | — | — | US | disclosed |
| US-20100310460-A1 | COMPOSITIONS AND METHODS FOR CHELATION THERAPY | LIU GANG | 2010-12-09 | — | — | US | disclosed |
| US-7728038-B2 | Methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-20060030619-A1 | Compositions and methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310460-A1 | COMPOSITIONS AND METHODS FOR CHELATION THERAPY | SOST, SOD3, HIF1AN | KDM4E 825/4885TP53 2100/4885CYP2D6 3640/4885 |
| US-20060030619-A1 | Compositions and methods for chelation therapy | SOST, SOD3, HIF1AN | KDM4E 825/4885TP53 2100/4885CYP2D6 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.