SCHEMBL254514

SCHEMBL254514

O=c1ccn(COCCO)c(=O)[nH]1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DUT P33316 7/20 0.56
ENPP1 P22413 4/20 0.55
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
UPP1 Q16831 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.45
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28776122 0.86 L3MBTL1 (0.54) DUTENPP1ALDH1A1LMNAL3MBTL1
SCHEMBL913298 0.82 DUT (0.56) DUTENPP1L3MBTL1PKM
SCHEMBL13573329 0.82 DUT (0.60) DUTENPP1L3MBTL1PKM
SCHEMBL7711032 0.80 PKM (0.58) DUTENPP1L3MBTL1PKM
SCHEMBL17230537 0.80 DUT (0.54) DUTENPP1ALDH1A1LMNAL3MBTL1
SCHEMBL2983407 0.79 ALDH1A1 (0.57) DUTALDH1A1LMNAL3MBTL1PKM
SCHEMBL12696994 0.79 DUT (0.57) DUTENPP1PKM
SCHEMBL13671537 0.79 DUT (0.57) DUTENPP1ALDH1A1LMNAPKM
SCHEMBL338055 0.79 ALDH1A1 (0.56) DUTENPP1ALDH1A1LMNAL3MBTL1
SCHEMBL7821648 0.78 DUT (0.63) DUTENPP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4916121-A PHOSPHORYLASE INHIBITOR TEIJIN LIMITED (JP) 1990-04-10 US claimed
EP-0202056-B1 ANTITUMOR AGENT TEIJIN LIMITED (JP) 1989-08-30 EP claimed
EP-0202056-A1 Antitumor agent TEIJIN LIMITED (JP) 1986-11-20 EP claimed
JP-61254526-A None JP disclosed
US-12419893-B2 Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine TOSK, INC. (US) 2025-09-23 US disclosed
US-12404304-B1 Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same SIERRA SCIENCES, LLC (US) 2025-09-02 US disclosed
US-20250222000-A1 Uridine Phosphorylase Inhibitors to Treat or Prevent Pulmonary Disease TOSK, INC. 2025-07-10 US disclosed
US-20250179122-A1 Telomerase Reverse Transcriptase (TERT) Expression Enhancing Compounds and Methods for Using the Same SIERRA SCIENCES, LLC 2025-06-05 US disclosed
US-20250120956-A1 Azole Compounds for Enhancing Telomerase Reverse Transcriptase (TERT) Expression SIERRA SCIENCES, INC. 2025-04-17 US disclosed
US-20250075198-A1 TETHERING CYSTEINE RESIDUES USING CYCLIC DISULFIDES BRANDEIS UNIVERSITY (US) 2025-03-06 US disclosed
US-20250049834-A1 Methods and Compositions for Treating Mucositis TOSK, INC. 2025-02-13 US disclosed
WO-1995012400-A1 NOVEL ENZYME INHIBITORS, THEIR SYNTHESIS, AND METHODS FOR USE UAB RESEARCH FOUNDATION (US) 1995-05-11 WO disclosed
WO-1993002044-A1 ACYCLIC 6-PHENYLSELENENYL PYRIMIDINE NUCLEOSIDES BAKER CUMMINS PHARMACEUTICALS, INC. (US) 1993-02-04 WO disclosed
US-4916121-A PHOSPHORYLASE INHIBITOR TEIJIN LIMITED (JP) 1990-04-10 US disclosed
US-4916121-A PHOSPHORYLASE INHIBITOR TEIJIN LIMITED (JP) 1990-04-10 US disclosed
US-4916121-A PHOSPHORYLASE INHIBITOR TEIJIN LIMITED (JP) 1990-04-10 US disclosed
EP-0202056-B1 ANTITUMOR AGENT TEIJIN LIMITED (JP) 1989-08-30 EP disclosed
EP-0202056-A1 Antitumor agent TEIJIN LIMITED (JP) 1986-11-20 EP disclosed
EP-0202056-A1 Antitumor agent TEIJIN LIMITED (JP) 1986-11-20 EP disclosed
JP-S61254526-A ANTITUMOR AGENT FOR ORAL ADMINISTRATION TEIJIN LTD 1986-11-12 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179122-A1 Telomerase Reverse Transcriptase (TERT) Expression Enhancing Compounds and Methods for Using the Same TERT, RNGTT, TERF2 DUT 56/4885ENPP1 571/4885ALDH1A1 1015/4885
US-12419893-B2 Methods and compositions for maximizing the prevention and/or reduction of various maladies and drug side-effects using uridine UMPS, UNG, UGDH DUT 7/4885ENPP1 65/4885ALDH1A1 289/4885
US-20250049834-A1 Methods and Compositions for Treating Mucositis UNG, UMPS, TYMP DUT 5/4885ENPP1 51/4885ALDH1A1 367/4885
US-20250075198-A1 TETHERING CYSTEINE RESIDUES USING CYCLIC DISULFIDES CDR2, TARDBP, CISD1 DUT 4573/4885ENPP1 4220/4885ALDH1A1 4293/4885
US-12404304-B1 Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same TERT, TELO2, POT1 DUT 291/4885ENPP1 1718/4885ALDH1A1 565/4885
US-20250120956-A1 Azole Compounds for Enhancing Telomerase Reverse Transcriptase (TERT) Expression TERT, ERG, TERF2 DUT 52/4885ENPP1 960/4885ALDH1A1 578/4885
US-20250222000-A1 Uridine Phosphorylase Inhibitors to Treat or Prevent Pulmonary Disease UPP1, UMPS, PNP DUT 60/4885ENPP1 34/4885ALDH1A1 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.