Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL1741544 | 0.85 | TSHR (0.70) | TSHRMEN1KMT2AKDM4EGAA | |
| Tetrahydrofuran SCHEMBL2502942 | 0.81 | TSHR (0.64) | TSHRMEN1KMT2ACHRM2CHRM4 | |
| Morpholine SCHEMBL28126679 | 0.79 | MEN1 (0.50) | TSHRMEN1KMT2AKDM4EGAA | |
| Morpholine SCHEMBL27737341 | 0.78 | GAA (0.61) | TSHRMEN1KMT2AKDM4EGAA | |
| Dioxane SCHEMBL4036904 | 0.78 | TSHR (0.58) | TSHRMEN1KMT2AGAACHRM2 | |
| SCHEMBL4977794 | 0.76 | TSHR (0.56) | TSHRMEN1KMT2AGAAMAPT | |
| Morpholine SCHEMBL23929419 | 0.75 | MEN1 (0.58) | TSHRMEN1KMT2AKDM4EGAA | |
| Morpholine SCHEMBL29207396 | 0.75 | KMT2A (0.58) | TSHRMEN1KMT2AKDM4EGAA | |
| Morpholine SCHEMBL219044 | 0.75 | KMT2A (0.58) | TSHRMEN1KMT2AKDM4EGAA | |
| SCHEMBL21064874 | 0.75 | TSHR (1.00) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838550-B2 | Selective N-sulfonylation of 2-amino fluoro- and trifluoroalkyl substituted alcohols | WYETH LLC (US) | 2010-11-23 | — | — | US | claimed |
| US-7687666-B2 | Methods for preparing sulfonamide substituted alcohols and intermediates thereof | WYETH (US) | 2010-03-30 | — | — | US | claimed |
| EP-1984321-A1 | METHODS FOR PREPARING SULFONAMIDE SUBSTITUTED ALCOHOLS AND INTERMEDIATES THEREOF | Wyeth (US) | 2008-10-29 | — | — | EP | claimed |
| WO-2007098029-A1 | METHODS FOR PREPARING SULFONAMIDE SUBSTITUTED ALCOHOLS AND INTERMEDIATES THEREOF | WYETH (US) | 2007-08-30 | — | — | WO | claimed |
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | WYETH (US) | 2007-08-23 | — | — | US | claimed |
| US-20070197830-A1 | Methods for preparing sulfonamide substituted alcohols and intermediates thereof | WYETH (US) | 2007-08-23 | — | — | US | claimed |
| US-7838550-B2 | Selective N-sulfonylation of 2-amino fluoro- and trifluoroalkyl substituted alcohols | WYETH LLC (US) | 2010-11-23 | — | — | US | disclosed |
| US-7687666-B2 | Methods for preparing sulfonamide substituted alcohols and intermediates thereof | WYETH (US) | 2010-03-30 | — | — | US | disclosed |
| EP-1984347-A1 | SELECTIVE N-SULFONYLATION OF 2-AMINO TRIFLUOROALKYL SUBSTITUTED ALCOHOLS | Wyeth a Corporation of the State of Delaware (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1984321-A1 | METHODS FOR PREPARING SULFONAMIDE SUBSTITUTED ALCOHOLS AND INTERMEDIATES THEREOF | Wyeth (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007098029-A1 | METHODS FOR PREPARING SULFONAMIDE SUBSTITUTED ALCOHOLS AND INTERMEDIATES THEREOF | WYETH (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007098030-A1 | SELECTIVE N-SULFONYLATION OF 2-AMINO TRIFLUOROALKYL SUBSTITUTED ALCOHOLS | WYETH (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | WYETH (US) | 2007-08-23 | — | — | US | disclosed |
| US-20070197830-A1 | Methods for preparing sulfonamide substituted alcohols and intermediates thereof | WYETH (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | BRAF, AFF2, SELENOI | TSHR 737/4885MEN1 1984/4885KMT2A 262/4885 |
| US-20070197830-A1 | Methods for preparing sulfonamide substituted alcohols and intermediates thereof | ADH1A, STS, ADH1C | TSHR 1736/4885MEN1 2965/4885KMT2A 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.