Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631933 | 0.82 | EPHX2 (0.52) | EPHX2CA12CA1CA9CYP1A2 | |
| SCHEMBL9424278 | 0.78 | ALDH1A1 (0.46) | EPHX2CA12CA1CA9CYP1A2 | |
| SCHEMBL10816873 | 0.75 | EPHX2 (0.59) | EPHX2ALDH1A1SIGMAR1KDM5AKDM4C | |
| SCHEMBL29407141 | 0.73 | EPHX2 (0.62) | EPHX2TSHRALDH1A1CES2CES1 | |
| SCHEMBL5253602 | 0.73 | CA12 (0.43) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL20625249 | 0.73 | EPHX2 (0.62) | EPHX2TSHRALDH1A1CES2CES1 | |
| SCHEMBL11634642 | 0.73 | EPHX2 (0.62) | EPHX2TSHRALDH1A1CES2CES1 | |
| SCHEMBL11046710 | 0.73 | EPHX2 (0.62) | EPHX2TSHRALDH1A1CES2CES1 | |
| SCHEMBL3310787 | 0.72 | ALDH1A1 (0.41) | EPHX2CA12CA1CA9ALDH1A1 | |
| SCHEMBL9423928 | 0.71 | EPHX2 (0.51) | EPHX2ALDH1A1SIGMAR1KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318160-B1 | Catalysts and process for the preparation of isocyanurate group containing polyisocyanates and their use | DEGUSSA (DE) | 2007-09-26 | — | — | EP | claimed |
| EP-1318152-B1 | Catalysts and process for preparing polyisocyanates containing isocyanurate groups | DEGUSSA (DE) | 2007-09-19 | — | — | EP | claimed |
| US-6875243-B2 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2005-04-05 | — | — | US | claimed |
| US-20030135007-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030109665-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-06-12 | — | — | US | claimed |
| US-4412073-A | Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-10-25 | — | — | US | claimed |
| US-8445622-B2 | Process for preparing polyisocyanates | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| US-20100292396-A1 | PROCESS FOR PREPARING POLYISOCYANATES | BASF SE (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100105833-A1 | WATER-EMULSIFIABLE POLYISOCYANATES | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| US-6875243-B2 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2005-04-05 | — | — | US | disclosed |
| US-20030135007-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-07-17 | — | — | US | disclosed |
| US-20030109665-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-06-12 | — | — | US | disclosed |
| US-4697014-A | Catalytic partial cyclotrimerization of polyisocyanates and product thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-09-29 | — | — | US | disclosed |
| US-4675401-A | Process for preparing polyisocyanato/polyisocyanurates by catalytic cyclotrimerization of polyisocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4537961-A | Catalytic cyclotrimerization of polyisocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-08-27 | — | — | US | disclosed |
| US-4412073-A | Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292396-A1 | PROCESS FOR PREPARING POLYISOCYANATES | PCBP1, ALKBH3, AGPS | EPHX2 377/4885CA12 1000/4885CA1 1250/4885 |
| US-20100105833-A1 | WATER-EMULSIFIABLE POLYISOCYANATES | AQP3, AQP1, AQP4 | EPHX2 78/4885CA12 1138/4885CA1 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.