SCHEMBL3318616

SCHEMBL3318616

CCCC[Si](C)(C)CCCO

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 3/20 0.48
TSHR P16473 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HSD17B10 Q99714 1/20 0.48
ACHE P22303 6/20 0.31
NAAA Q02083 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
DNM1 Q05193 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7517899 0.92 SMN1; SMN2 (0.55) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL8135195 0.90 LMNA (0.57) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL11147938 0.90 LMNA (0.57) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL11125950 0.90 LMNA (0.57) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL9034708 0.89 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL10519281 0.88 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL10397542 0.85 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL11418684 0.85 TSHR (0.43) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL10966146 0.84 LMNA (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1
SCHEMBL11364943 0.84 LMNA (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4029993-A None JP disclosed
US-8460069-B2 Lens holder HOYA CORPORATION (JP) 2013-06-11 US disclosed
US-8216024-B2 Spectacle lens edging method HOYA CORPORATION (JP) 2012-07-10 US disclosed
EP-2140971-B1 LENS HOLDER HOYA CORP (JP) 2012-05-23 EP disclosed
US-20100112915-A1 LENS HOLDER HOYA CORPORATION (JP) 2010-05-06 US disclosed
US-20100105293-A1 SPECTACLE LENS EDGING METHOD HOYA CORPORATION (JP) 2010-04-29 US disclosed
EP-2140971-A1 LENS HOLDER Hoya Corporation (JP) 2010-01-06 EP disclosed
EP-2138269-A1 METHOD FOR EDGING LENS OF GLASSES Hoya Corporation (JP) 2009-12-30 EP disclosed
US-7318959-B2 Optical element having antireflection film HOYA CORPORATION (JP) 2008-01-15 US disclosed
CN-1276275-C Optical element with anti reflective film HOYA CORP (JP) 2006-09-20 CN disclosed
CN-1512196-A Optical element with anti reflective film ������������ʽ���� 2004-07-14 CN disclosed
EP-1433809-A1 Optical member having antireflection film HOYA CORPORATION (JP) 2004-06-30 EP disclosed
EP-0476567-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-06-12 EP disclosed
EP-0458320-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-01-04 EP disclosed
US-5217645-A Low temperature, high speed response CANON KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed
US-5188762-A Ferroelectric liquid crystal with high response speed and small temperature dependence CANON KABUSHIKI KAISHA (JP) 1993-02-23 US disclosed
EP-0476567-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-03-25 EP disclosed
JP-H0429993-A LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND LIQUID CRYSTAL ELEMENT USING THE SAME CANON INC 1992-01-31 JP disclosed
EP-0458320-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1991-11-27 EP disclosed
US-4267172-A PRODUCED BY REACTING A TRIORGANOSILYL ALCOHOL WITH PHOSPHORUS TRICHLORIDE SHIN-ETSU CHEMICAL CO. LTD. (JP) 1981-05-12 US disclosed