Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19134049 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL19134045 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL19134051 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL19134054 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL3318616 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL7517899 | 0.86 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL11418684 | 0.85 | TSHR (0.43) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL8135195 | 0.84 | LMNA (0.57) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL10524658 | 0.82 | — | — | |
| SCHEMBL3314375 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |