Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331867 | 0.87 | TSHR (0.38) | — | |
| SCHEMBL23493061 | 0.85 | TSHR (0.38) | ALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL331865 | 0.84 | — | — | |
| SCHEMBL30306612 | 0.81 | USP2 (0.47) | USP2 | |
| SCHEMBL509069 | 0.80 | — | — | |
| Methacrylic Acid SCHEMBL2125330 | 0.80 | USP2 (0.38) | USP2ALDH1A1 | |
| SCHEMBL508665 | 0.78 | — | — | |
| SCHEMBL508852 | 0.78 | — | — | |
| SCHEMBL1960031 | 0.76 | MAPT (0.30) | MAPT | |
| SCHEMBL529602 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250263512-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2025-08-21 | — | — | US | disclosed |
| CN-115698190-B | Light stability simulation of macular pigment | 强生视力健公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-112437889-B | Silicone hydrogel contact lenses with non-uniform morphology | 强生视力健公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114096514-B | Polymerizable amino acid-based compounds and ophthalmic devices made therefrom | 强生视力健公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114144248-B | Imidazolium zwitterionic polymerizable compounds and ophthalmic devices incorporating same | 强生视力健公司 | 2025-06-03 | — | — | CN | disclosed |
| US-20250075024-A1 | OPHTHALMIC DEVICES CONTAINING LOCALIZED GRAFTED NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE (US) | 2025-03-06 | — | — | US | disclosed |
| CN-119365797-A | Ophthalmic devices comprising light stable mimics of macular pigments and other visible light filters | 强生视力健公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-113874781-B | Contact lens comprising photosensitive chromophore and package therefor | 强生视力健公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119173379-A | Ophthalmic lens and its manufacture by in-mold modification | 强生视力健公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-112449635-B | Polymerizable fused tricyclic compounds as UV and visible light absorbers | 强生视力健公司 | 2024-10-29 | — | — | CN | disclosed |
| US-20130317132-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2013-11-28 | — | — | US | disclosed |
| US-20130317131-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| US-8222353-B2 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20110294914-A1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. | 2011-12-01 | — | — | US | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |
| US-8022158-B2 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-7786185-B2 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100151123-A1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. | 2010-06-17 | — | — | US | disclosed |
| EP-1720943-B1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2009-02-11 | — | — | EP | disclosed |
| US-20080045612-A1 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151123-A1 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES | CRYAA, UACA, CRYZ | USP2 360/4885ALDH1A1 4436/4885CYP3A4 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.