Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 3/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 3/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421042 | 0.83 | LGALS3 (0.50) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL7027211 | 0.81 | CA1 (0.42) | PTPN1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL24672150 | 0.80 | NT5E (0.52) | PTPN1NT5EPTPN2PTPN6PTPN11 | |
| SCHEMBL7026503 | 0.79 | LGALS3 (0.38) | PTPN1NT5ELGALS9LGALS1LGALS3 | |
| SCHEMBL17073909 | 0.78 | LGALS9 (0.40) | PTPN1PTPN2PTPN11LGALS9LGALS1 | |
| SCHEMBL17889788 | 0.77 | LGALS3 (0.46) | NT5ELGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL21076164 | 0.77 | LGALS3 (0.46) | NT5ELGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL17889789 | 0.77 | LGALS3 (0.46) | NT5ELGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL17897127 | 0.77 | LGALS3 (0.46) | NT5ELGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL7024119 | 0.77 | NT5E (0.43) | PTPN1NT5EPTPN2PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338387-B2 | Small molecule stimulators of neuronal growth | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100075920-A1 | SMALL MOLECULE STIMULATORS OF NEURONAL GROWTH | NATIONAL SCIENCE FOUNDATION | 2010-03-25 | — | — | US | disclosed |
| US-7638503-B2 | Small molecule stimulators of neuronal growth | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-12-29 | — | — | US | disclosed |
| US-20060025379-A1 | Small molecule stimulators of neuronal growth | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025379-A1 | Small molecule stimulators of neuronal growth | BDNF, GAP43, NGF | PTPN1 4118/4885NT5E 3124/4885PTPN2 3735/4885 |
| US-20100075920-A1 | SMALL MOLECULE STIMULATORS OF NEURONAL GROWTH | BDNF, GAP43, NGF | PTPN1 4118/4885NT5E 3124/4885PTPN2 3735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.