Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13333114 | 0.93 | HSD11B1 (0.59) | HPGDALDH1A1POLBKDM4EHSD11B1 | |
| SCHEMBL3323868 | 0.86 | HSD11B1 (0.59) | HPGDALDH1A1POLBKDM4EHSD11B1 | |
| SCHEMBL3321983 | 0.78 | HSD11B1 (0.61) | HPGDALDH1A1POLBHSD11B1LMNA | |
| SCHEMBL14142610 | 0.76 | LMNA (0.80) | HPGDALDH1A1POLBKDM4EHSD11B1 | |
| SCHEMBL1525284 | 0.76 | SMN1; SMN2 (0.54) | HPGDALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL31439281 | 0.76 | HPGD (0.65) | HPGDALDH1A1POLBKDM4EHSD11B1 | |
| SCHEMBL5119029 | 0.75 | TSHR (0.63) | HPGDALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL22365557 | 0.75 | HPGD (0.62) | HPGDALDH1A1POLBKDM4EHSD11B1 | |
| SCHEMBL3325060 | 0.75 | HSD11B1 (0.62) | HPGDALDH1A1POLBKDM4EHSD11B1 | |
| SCHEMBL8009042 | 0.73 | HPGD (0.66) | HPGDALDH1A1POLBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | HPGD 330/4885ALDH1A1 437/4885POLB 1708/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | HPGD 3581/4885ALDH1A1 3143/4885POLB 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.