Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL332037

CCCC[N+](CCCC)(CCCC)CCCC.O=S(=O)(O)c1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
TDP1 Q9NUW8 1/20 0.46
PSIP1 O75475 1/20 0.44
SLC22A1 O15245 1/20 0.43
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.42
S1PR3 Q99500 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
EPHX2 P34913 1/20 0.41
NAAA Q02083 3/20 0.40
PTGS2 P35354 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CNR2 P34972 1/20 0.40
HSD11B1 P28845 1/20 0.40
MMP1 P03956 1/20 0.39
MMP7 P09237 1/20 0.39
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330758 0.97 SMN1; SMN2 (0.53) TSHRSMN1; SMN2TDP1PSIP1SLC22A1
SCHEMBL330870 0.95 SMN1; SMN2 (0.55) TSHRSMN1; SMN2TDP1PSIP1SLC22A1
SCHEMBL330956 0.95 SMN1; SMN2 (0.55) TSHRSMN1; SMN2TDP1PSIP1SLC22A1
Tetrahexylammonium SCHEMBL331918 0.95 SMN1; SMN2 (0.55) TSHRSMN1; SMN2TDP1PSIP1SLC22A1
Nonane SCHEMBL30043094 0.91 SMN1; SMN2 (0.64) TSHRSMN1; SMN2TDP1PSIP1POLB
Hexane SCHEMBL27501792 0.91 TSHR (0.70) TSHRSMN1; SMN2TDP1PSIP1POLB
SCHEMBL330304 0.90 DNM1 (0.50) TSHRSMN1; SMN2TDP1SLC22A1CYP2D6
SCHEMBL332183 0.90 DNM1 (0.50) TSHRSMN1; SMN2TDP1SLC22A1CYP2D6
Tetrapropylammonium SCHEMBL332360 0.89 TSHR (0.61) TSHRSMN1; SMN2TDP1PSIP1SLC22A1
SCHEMBL331062 0.89 SMN1; SMN2 (0.48) TSHRSMN1; SMN2TDP1PSIP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109276569-B Stable crystal form pharmaceutical composition and preparation method and application thereof 四川海思科制药有限公司 2020-09-29 CN claimed
CN-109276569-A A kind of stable crystal form pharmaceutical composition and its preparation method and application 四川海思科制药有限公司 2019-01-29 CN claimed
EP-2116558-B1 POLYMERIZABLE COMPOSITION CONTAINING A CATALYST, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND METHOD FOR PRODUCING THE OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2017-01-18 EP claimed
US-20100016517-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANE-BASED OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE CATALYST, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND METHOD FOR PREPARING THE OPTICAL MATERIAL MITSUI CHEMICALS, INC (JP) 2010-01-21 US claimed
EP-2116558-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE CATALYST, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND METHOD FOR PRODUCING THE OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2009-11-11 EP claimed
US-5356748-A Nonaqueous solvent containing dispersed resin grains and graft polymer stabilizer FUJI PHOTO FILM CO., LTD. (JP) 1994-10-18 US claimed
CN-109276569-B Stable crystal form pharmaceutical composition and preparation method and application thereof 四川海思科制药有限公司 2020-09-29 CN disclosed
CN-109276569-A A kind of stable crystal form pharmaceutical composition and its preparation method and application 四川海思科制药有限公司 2019-01-29 CN disclosed
EP-2780387-B1 POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE MITSUI CHEMICALS INC (JP) 2018-11-07 EP disclosed
EP-2295484-B1 POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM SAME POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2018-01-17 EP disclosed
EP-2407498-B1 Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material MITSUI CHEMICALS INC (JP) 2017-11-15 EP disclosed
EP-2116558-B1 POLYMERIZABLE COMPOSITION CONTAINING A CATALYST, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND METHOD FOR PRODUCING THE OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2017-01-18 EP disclosed
US-9527948-B2 Polymerizable composition, optical article obtained therefrom and method for the production of said optical article MITSUI CHEMICALS, INC. (JP) 2016-12-27 US disclosed
CN-1198444-A Method for producing crosslinked polyaspartic acid resin MITSUI CHEMICALS INC (JP) 1998-11-11 CN disclosed
EP-0866084-A2 Production process of cross-linked polyaspartic acid resin Mitsui Chemicals, Inc. (JP) 1998-09-23 EP disclosed
US-5589312-A RESIN GRAINS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-31 US disclosed
US-5532099-A RESIN GRAINS DISPERSED IN A NONAQUEOUS SOLVENT POLYMERIZED IN PRESENCE OF DISPERSION STABILIZING RESIN; TONER IMAGES HAVING RESIST WITH ETCHING RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-07-02 US disclosed
EP-0678552-A1 Process for the preparation of modified polybutylene terephthalate resin POLYPLASTICS CO. LTD. (JP) 1995-10-25 EP disclosed
US-5356748-A Nonaqueous solvent containing dispersed resin grains and graft polymer stabilizer FUJI PHOTO FILM CO., LTD. (JP) 1994-10-18 US disclosed
US-5308730-A Liquid developer for electrostatic photography FUJI PHOTO FILM CO., LTD. (JP) 1994-05-03 US disclosed