SCHEMBL3320669

SCHEMBL3320669

CC(C)(CN)CC(=O)N1CCC(Oc2ccc(CO)cc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KMT2A Q03164 3/20 0.47
LIPE Q05469 1/20 0.43
GPR119 Q8TDV5 2/20 0.43
POLB P06746 2/20 0.42
MLNR O43193 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3320206 0.79 L3MBTL1 (0.46) L3MBTL1LIPEMAPTLMNA
SCHEMBL3342716 0.78 GPR119 (0.66) GPR119
SCHEMBL3320665 0.78 HRH2 (0.47) L3MBTL1KMT2ALIPEGPR119POLB
SCHEMBL13361619 0.78 HRH2 (0.47) L3MBTL1KMT2ALIPEGPR119POLB
SCHEMBL3348834 0.77 EPHX2 (0.48) KMT2ALMNA
SCHEMBL26644531 0.72 HRH3 (0.58)
SCHEMBL3342725 0.72 GPR119 (0.61) GPR119
SCHEMBL3320075 0.72 POLB (0.62) KMT2APOLBLMNA
SCHEMBL6135696 0.71 ALDH1A1 (0.62) L3MBTL1KMT2A
SCHEMBL3342770 0.71 GPR119 (0.59) GPR119LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100125075-A1 Antibacterial Agents BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2010-05-20 US disclosed
US-7186719-B2 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS (GB) 2007-03-06 US disclosed
US-20050065095-A1 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2005-03-24 US disclosed
US-6846825-B1 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2005-01-25 US disclosed
EP-1202968-A2 ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2002-05-08 EP disclosed
WO-2001010834-A9 ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARM (GB) 2001-08-09 WO disclosed
WO-2001010834-A2 ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065095-A1 Antibacterial agents NQO2, DAO, Q6ZSR9 L3MBTL1 2349/4885KMT2A 3765/4885LIPE 3768/4885
US-20100125075-A1 Antibacterial Agents NQO2, DAO, Q6ZSR9 L3MBTL1 1972/4885KMT2A 3725/4885LIPE 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.