Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674781 | 0.88 | ALDH1A1 (0.41) | TSHRALDH1A1AKT1ESR1ESR2 | |
| SCHEMBL49494 | 0.80 | ESR1 (0.42) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| Formaldehyde SCHEMBL8724973 | 0.78 | ESR1 (0.37) | TSHRALDH1A1AKT1ESR1ESR2 | |
| SCHEMBL709944 | 0.77 | ESR1 (0.40) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| SCHEMBL28443818 | 0.77 | ESR1 (0.40) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| SCHEMBL27700114 | 0.77 | ESR1 (0.40) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| SCHEMBL9345851 | 0.77 | ESR1 (0.40) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| Hydrochloric Acid SCHEMBL28156324 | 0.77 | ESR1 (0.40) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| SCHEMBL28289364 | 0.77 | ESR1 (0.40) | TSHRALDH1A1ESR1ESR2ALOX15 | |
| SCHEMBL3813640 | 0.76 | ALDH1A1 (0.54) | TSHRALDH1A1AKT1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8460069-B2 | Lens holder | HOYA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8216024-B2 | Spectacle lens edging method | HOYA CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| EP-2140971-B1 | LENS HOLDER | HOYA CORP (JP) | 2012-05-23 | — | — | EP | disclosed |
| US-20100112915-A1 | LENS HOLDER | HOYA CORPORATION (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100105293-A1 | SPECTACLE LENS EDGING METHOD | HOYA CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2140971-A1 | LENS HOLDER | Hoya Corporation (JP) | 2010-01-06 | — | — | EP | disclosed |
| EP-2138269-A1 | METHOD FOR EDGING LENS OF GLASSES | Hoya Corporation (JP) | 2009-12-30 | — | — | EP | disclosed |