Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904668 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| SCHEMBL7036486 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL30464098 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL7034247 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL7036471 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL7036128 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL49494 | 0.78 | ESR1 (0.42) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL1109011 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| Formaldehyde SCHEMBL8724973 | 0.76 | ESR1 (0.37) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL3321240 | 0.76 | TSHR (0.33) | ALDH1A1TSHRESR1ESR2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117264423-A | Semiconductor nanocrystal-siloxane composite resin compound and preparation method and application thereof | 苏州星烁纳米科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| US-10544359-B2 | Method for preparing semiconductor nanocrystal siloxane composite resin composition | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-01-28 | — | — | US | claimed |
| US-20180273838-A1 | METHOD FOR PREPARING SEMICONDUCTOR NANOCRYSTAL SILOXANE COMPOSITE RESIN COMPOSITION | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-09-27 | — | — | US | claimed |
| US-9884879-B2 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2018-02-06 | — | — | US | claimed |
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2017-03-30 | — | — | US | claimed |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | SILECS OY (FI) | 2014-09-04 | — | — | US | claimed |
| US-20130165615-A1 | PROCESS FOR PRODUCING POLYSILOXANES AND USE OF THE SAME | ZETTA RESEARCH AND DEVELOPMENT LLC - RPO SERIES (US) | 2013-06-27 | — | — | US | claimed |
| WO-2012172176-A9 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2013-02-07 | — | — | WO | claimed |
| WO-2012172176-A2 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2012-12-20 | — | — | WO | claimed |
| EP-2078051-A1 | PROCESS FOR PRODUCING POLYSILOXANES AND USE OF THE SAME | RPO PTY Limited (AU) | 2009-07-15 | — | — | EP | claimed |
| US-20090088547-A1 | Process for producing polysiloxanes and use of the same | RPO PTY LIMITED (AU) | 2009-04-02 | — | — | US | claimed |
| WO-2008046142-A1 | PROCESS FOR PRODUCING POLYSILOXANES AND USE OF THE SAME | RPO PTY LIMITED (AU) | 2008-04-24 | — | — | WO | claimed |
| CN-117264423-A | Semiconductor nanocrystal-siloxane composite resin compound and preparation method and application thereof | 苏州星烁纳米科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-10544359-B2 | Method for preparing semiconductor nanocrystal siloxane composite resin composition | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-01-28 | — | — | US | disclosed |
| US-20180273838-A1 | METHOD FOR PREPARING SEMICONDUCTOR NANOCRYSTAL SILOXANE COMPOSITE RESIN COMPOSITION | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-09-27 | — | — | US | disclosed |
| US-9884879-B2 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2018-02-06 | — | — | US | disclosed |
| WO-2003104304-A1 | METHOD FOR MAKING SILOXANE POLYMERS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2003-12-18 | — | — | WO | disclosed |
| US-20030232951-A1 | Preparation of low loss optical material from difunctional silyl enol ethers and difunctional silanols | AUSTRALIAN NATIONAL UNIVERSITY, THE (AU) | 2003-12-18 | — | — | US | disclosed |
| WO-2003097719-A1 | IMPROVEMENT OF LOW LOSS OPTICAL MATERIAL | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2003-11-27 | — | — | WO | disclosed |
| US-20030216537-A1 | LOW LOSS OPTICAL MATERIAL | AUSTRALIAN NATIONAL UNIVERSITY, THE (AU) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | MSMO1, PCNA, PIEZO1 | ALDH1A1 345/4885TSHR 4868/4885TDP1 3850/4885 |
| US-20030232951-A1 | Preparation of low loss optical material from difunctional silyl enol ethers and difunctional silanols | CNKSR1, CCNL2, SAAL1 | ALDH1A1 461/4885TSHR 3837/4885TDP1 4316/4885 |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | MSMO1, PCNA, PIEZO1 | ALDH1A1 345/4885TSHR 4868/4885TDP1 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.