SCHEMBL332135

SCHEMBL332135

CS(=O)(=O)O.C[N+](C)(C)Cc1ccccc1

nearest known ligand 0.68

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B known ✓ Q13224 1/20 0.39
ALDH1A1 P00352 3/20 0.68
KDM4E B2RXH2 2/20 0.68
TDP1 Q9NUW8 1/20 0.68
CYP3A4 P08684 2/20 0.44
GAA P10253 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
BLM P54132 1/20 0.44
GFER P55789 1/20 0.44
PMP22 Q01453 1/20 0.44
CA2 P00918 4/20 0.44
CA1 P00915 3/20 0.44
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL229800 0.94 KDM4E (0.71) ALDH1A1KDM4ETDP1CYP3A4GAA
Sulfuric Acid SCHEMBL7637641 0.92 KDM4E (0.68) ALDH1A1KDM4ETDP1CYP3A4GAA
Sulfuric Acid SCHEMBL229801 0.90 KDM4E (0.65) ALDH1A1KDM4ETDP1CYP3A4GAA
Thiosulfuric Acid SCHEMBL8424194 0.90 KDM4E (0.65) ALDH1A1KDM4ETDP1CYP3A4GAA
SCHEMBL330945 0.90 KDM4E (0.65) ALDH1A1KDM4ETDP1CYP3A4GAA
SCHEMBL331216 0.88 ALDH1A1 (0.63) ALDH1A1KDM4ETDP1CYP3A4GAA
SCHEMBL332134 0.88 KDM4E (0.68) ALDH1A1KDM4ETDP1CYP3A4CA2
Sulfuric Acid SCHEMBL229799 0.85 KDM4E (0.71) ALDH1A1KDM4ETDP1CYP3A4CA2
Vinylsulfonic Acid SCHEMBL9519686 0.85 ALDH1A1 (0.59) ALDH1A1KDM4ETDP1CYP3A4GAA
Trifluoromethanesulfonic Acid SCHEMBL1130294 0.85 ALDH1A1 (0.59) ALDH1A1KDM4ETDP1CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2295484-B1 POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM SAME POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2018-01-17 EP disclosed
EP-2407498-B1 Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material MITSUI CHEMICALS INC (JP) 2017-11-15 EP disclosed
US-8304507-B2 Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material MITSUI CHEMICALS, INC. (JP) 2012-11-06 US disclosed
EP-2407498-A2 Polymerizable composition for polythiourethane optical material, polythiourethane optical material obtained from the polymerizable composition, and polymerization catalyst for polythiourethane optical material Mitsui Chemicals, Inc. (JP) 2012-01-18 EP disclosed
US-20110112269-A1 POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM THE POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2011-05-12 US disclosed
EP-2295484-A1 POLYMERIZABLE COMPOSITION FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYTHIOURETHANE OPTICAL MATERIAL OBTAINED FROM SAME POLYMERIZABLE COMPOSITION, AND POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2011-03-16 EP disclosed
EP-1680806-A4 CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME SACHEM INC (US) 2008-07-30 EP disclosed
US-7192910-B2 Cleaning solutions and etchants and methods for using same SACHEM, INC. (US) 2007-03-20 US disclosed
EP-1680806-A2 CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME Sachem, Inc. (US) 2006-07-19 EP disclosed
US-20050143270-A1 Cleaning solutions and etchants and methods for using same SACHEM, INC. 2005-06-30 US disclosed
WO-2005045895-A2 CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME SACHEM, INC. (US) 2005-05-19 WO disclosed