Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | JUN | P05412 | 1/20 | 0.70 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | GUSB | P08236 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 5/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3321477 | 1.00 | NFKB1 (0.70) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL6907589 | 0.87 | NFKB1 (0.50) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL1160537 | 0.83 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL1160535 | 0.83 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL3329177 | 0.83 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| SCHEMBL29539991 | 0.83 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| O-Coumaric Acid SCHEMBL29367602 | 0.81 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| O-Coumaric Acid SCHEMBL29368085 | 0.81 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| O-Coumaric Acid SCHEMBL64885 | 0.81 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 | |
| O-Coumaric Acid SCHEMBL892006 | 0.81 | NFKB1 (1.00) | NFKB1JUNNFE2L2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741337-B2 | Azonafide derivatives, methods for their production and pharmaceutical compositions therefrom | UNIBIOSCREEN S.A. (BE) | 2010-06-22 | — | — | US | disclosed |
| US-20080292585-A1 | Azonafide Derivatives, Methods for Their Production and Pharmaceutical Compositions Therefrom | UNIBIOSCREEN S.A. (BE) | 2008-11-27 | — | — | US | disclosed |
| EP-1787985-A1 | Azonafide derivatives, methods for their production and pharmaceutical compositions therefrom | Unibioscreen S.A. (BE) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292585-A1 | Azonafide Derivatives, Methods for Their Production and Pharmaceutical Compositions Therefrom | AADAC, NOTUM, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | NFKB1 1071/4885JUN 3531/4885NFE2L2 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.