Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390592 | 0.87 | HDAC1 (0.65) | NFKB1HDAC1HDAC8HDAC6GSR | |
| SCHEMBL1569435 | 0.87 | HDAC1 (0.65) | NFKB1HDAC1HDAC8HDAC6GSR | |
| SCHEMBL3321477 | 0.87 | NFKB1 (0.70) | NFKB1NFE2L2JUNCA1CA2 | |
| SCHEMBL3321487 | 0.87 | NFKB1 (0.70) | NFKB1NFE2L2JUNCA1CA2 | |
| SCHEMBL1569438 | 0.87 | HDAC1 (0.65) | NFKB1HDAC1HDAC8HDAC6GSR | |
| SCHEMBL6421789 | 0.85 | ALDH1A1 (0.48) | NFKB1NFE2L2JUNCA1CA2 | |
| SCHEMBL6583886 | 0.85 | NFE2L2 (0.58) | NFE2L2MAPTLMNANPC1RAB9A | |
| SCHEMBL9780865 | 0.85 | HSD11B1 (0.71) | NFKB1NFE2L2JUNCA1CA2 | |
| SCHEMBL7069601 | 0.85 | ALDH1A1 (0.48) | NFKB1NFE2L2JUNCA1CA2 | |
| SCHEMBL9780869 | 0.85 | HSD11B1 (0.71) | NFKB1NFE2L2JUNCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689899-B2 | HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20020019558-A1 | Diamine and acid anhydride | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-14 | — | — | US | disclosed |
| US-6303742-B1 | CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. | KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-10-16 | — | — | US | disclosed |
| US-6294593-B1 | COMBINING HOST POLYMER WITH GUEST CROSSLINIKING AGENT; EXPOSING COMBINED HOST POLYMER AND GUEST CROSSLINKING AGENT TO ELECTRIC FIELD TO POLE SECOND ORDER NONLINEAR OPTICAL COMPONENT OF POLYMER; EXPOSING TO ELECTROMAGNETIC RADIATION | UNIVERSITY OF MASSACHUSETTS LOWELL | 2001-09-25 | — | — | US | disclosed |
| EP-0045694-B1 | TWO-SHEET DIFFUSION TRANSFER PHOTOGRAPHIC ASSEMBLAGES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0045693-B1 | PHOTOGRAPHIC ELEMENT FOR TWO-SHEET DIFFUSION TRANSFER PHOTOGRAPHY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4346160-A | OVERCAOTING PREVENTS PREMATURE DELAMINATION | EASTMAN KODAK COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| EP-0045693-A2 | Photographic element for two-sheet diffusion transfer photography | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-02-10 | — | — | EP | disclosed |
| EP-0045694-A2 | Two-sheet diffusion transfer photographic assemblages | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-02-10 | — | — | EP | disclosed |
| US-4298682-A | PREVENTION OF SPONTANEOUS DELAMINATION | EASTMAN KODAK COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| US-4297432-A | CONTAINING A VINYLIDENE CHLORIDE POLYMERIC LAYER, AN ANIONIC POLYESTER LAYER AND A CATIONIC ACRYLIC ESTER OR AMIDE POLYMER LAYER | EASTMAN KODAK COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019558-A1 | Diamine and acid anhydride | CA1, ASIC1, CA4 | NFKB1 2872/4885NFE2L2 1523/4885JUN 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.